Evidence map›Paper›PMID 26099112›Full record

ArticleNature materials2015

Dynamic polymer systems with self-regulated secretion for the control of surface properties and material healing.

Jiaxi Cui, Daniel Daniel, Alison Grinthal, Kaixiang Lin, Joanna Aizenberg

Open access · greenAbstract read
PubMed Publisher
In one paragraph

Article in Nature materials, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
13.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 286 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Supramolecular Lubricating Hydrogel Microspheres Reshape Damaged Matrix Regeneration.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Bioinspired liquid-infused surface for biomedical and biosensing applications.Frontiers in bioengineering and biotechnology · 2022
    Review
  10. Dynamic Anti-Icing Surfaces (DAIS).Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2021
    Review
  11. Article
  12. Solar anti-icing surface with enhanced condensate self-removing at extreme environmental conditions.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Recent Advances in Bioinspired Gel Surfaces with Superwettability and Special Adhesion.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2019
    Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Jiaxi Cui1] School of Engineering and Applied Sciences, Harvard University, Cambridge, Massachusetts 02138, USA [2] Wyss Institute for Biologically Inspired Engineering, Harvard University, Cambridge, Massachusetts 02138, USA.
Daniel DanielSchool of Engineering and Applied Sciences, Harvard University, Cambridge, Massachusetts 02138, USA.
Alison GrinthalSchool of Engineering and Applied Sciences, Harvard University, Cambridge, Massachusetts 02138, USA.
Kaixiang LinDepartment of Chemistry and Chemical Biology, Harvard University, Cambridge, Massachusetts 02138, USA.
Joanna Aizenberg1] School of Engineering and Applied Sciences, Harvard University, Cambridge, Massachusetts 02138, USA [2] Wyss Institute for Biologically Inspired Engineering, Harvard University, Cambridge, Massachusetts 02138, USA [3] Department of Chemistry and Chemical Biology, Harvard University, Cambridge, Massachusetts 02138, USA [4] Kavli Institute for Bionano Science and Technology, Harvard University, Cambridge, Massachusetts 02138, USA.
Harvard University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Approaches for regulated fluid secretion, which typically rely on fluid encapsulation and release from a shelled compartment, do not usually allow a fine continuous modulation of secretion, and can be difficult to adapt for monitoring or function-integration purposes. Here, we report self-regulated, self-reporting secretion systems consisting of liquid-storage compartments in a supramolecular polymer-gel matrix with a thin liquid layer on top, and demonstrate that dynamic liquid exchange between the compartments, matrix and surface layer allows repeated, responsive self-lubrication of the surface and cooperative healing of the matrix. Depletion of the surface liquid or local material damage induces secretion of the stored liquid via a dynamic feedback between polymer crosslinking, droplet shrinkage and liquid transport that can be read out through changes in the system's optical transparency. We foresee diverse applications in fluid delivery, wetting and adhesion control, and material self-repair.

Indexed as

Biocompatible MaterialsDimethylpolysiloxanesGelsImaging, Three-DimensionalMaterials TestingPolymersSolventsSpectrophotometryStress, MechanicalSurface PropertiesUreabaysilonBiocompatible MaterialsDimethylpolysiloxanesGelsPolymersSolventsUrea

Identifiers

PMID26099112
OpenAlexW769344510

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.