Evidence map›Paper›PMID 26098965›Full record

ReviewExpert review of clinical immunology2015

Immunomodulatory role of vitamin D in the pathogenesis of preeclampsia.

Tyler A Smith, Daniel R Kirkpatrick, Oormila Kovilam, Devendra K Agrawal

Abstract readReview
In one paragraph

Review in Expert review of clinical immunology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 34 citations in OpenAlex.

  1. Article
  2. TNF-Expert reviews in molecular medicine · 2022
    Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Immunometabolism, pregnancy, and nutrition.Seminars in immunopathology · 2018
    Review
  11. Long Non-Coding RNAs Serve as Diagnostic Biomarkers of Preeclampsia and Modulate Migration and Invasiveness of Trophoblast Cells.Medical science monitor : international medical journal of experimental and clinical research · 2018
    Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Tyler A SmithCenter for Clinical & Translational Science, Creighton University School of Medicine, Omaha, NE, USA.
Daniel R Kirkpatrick
Oormila Kovilam
Devendra K Agrawal
Creighton University · US

Funding

MESENCHYMAL STEM CELLS IN THE PREVENTION OF THROMBOSIS AND NEOINTIMAL HYPERPLASIAR01HL112597 · NHLBI · CREIGHTON UNIVERSITY · PI AGRAWAL, DEVENDRA K. · 2012 to 2016
$3.8M
EPICARDIAL ADIPOSE TISSUE, OBESITY AND INFLAMMATION IN ATHEROSCLEROSISR01HL120659 · NHLBI · CREIGHTON UNIVERSITY · PI AGRAWAL, DEVENDRA K. · 2013 to 2017
$3.6M
VITAMIN D AND IMMUNOMODULATION IN CORONARY ARTERY DISEASER01HL116042 · NHLBI · CREIGHTON UNIVERSITY · PI AGRAWAL, DEVENDRA K. · 2012 to 2016
$3.3M
GENE AND STEM CELL THERAPY IN CORONARY ARTERY BYPASS GRAFTR01HL128063 · NHLBI · CREIGHTON UNIVERSITY · PI AGRAWAL, DEVENDRA K. · 2015 to 2018
$2.9M
Renal Medullary Stem Cell Niche in Salt Sensitive HypertensionR01HL106042 · NHLBI · VIRGINIA COMMONWEALTH UNIVERSITY · PI LI, NINGJUN · 2011 to 2014
$1.5M
NHLBI NIH HHS R01 HL106042NHLBI NIH HHS R01 HL112597NHLBI NIH HHS R01 HL116042NHLBI NIH HHS R01 HL120659NHLBI NIH HHS R01 HL128063
6 · The paper itself

Abstract

Worldwide, preeclampsia is a significant health risk to both pregnant women and their unborn children. Despite scientific advances, the exact pathogenesis of preeclampsia is not yet fully understood. Meanwhile, the incidence of preeclampsia is expected to increase. A series of potential etiologies for preeclampsia has been identified, including endothelial dysfunction, immunological dysregulation and trophoblastic invasion. In this literature review, we have critically reviewed existing literature regarding the research findings that link the role of vitamin D to the pathogenesis and immunoregulation of preeclampsia. The relationship of vitamin D with the suspected etiologies of preeclampsia underscores its clinical potential in the diagnosis and treatment of preeclampsia.

Indexed as

Anti-Inflammatory Agents, Non-SteroidalAspirinFemaleHumansPractice Guidelines as TopicPre-EclampsiaPregnancyT-LymphocytesVitamin DVitamin D DeficiencyVitaminsAnti-Inflammatory Agents, Non-SteroidalAspirinVitamin DVitaminscathelicidinendothelial dysfunctionimmunomodulationpreeclampsiavitamin D

Identifiers

PMID26098965
PMCPMC4829935
OpenAlexW1931264825

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.