Evidence map›Paper›PMID 26098945›Full record

ReviewTranscription2015

Valuable lessons-learned in transcriptomics experimentation.

Oskar Bruning, Han Rauwerda, Rob J Dekker, Wim C de Leeuw, Paul F K Wackers, Wim A Ensink, Martijs J Jonker, Timo M Breit

Abstract readReview
In one paragraph

Review in Transcription, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Oskar Bruninga RNA Biology & Applied Bioinformatics research group; Swammerdam Institute for Life Sciences; Faculty of Science; University of Amsterdam ; Amsterdam , the Netherlands.
Han Rauwerda
Rob J Dekker
Wim C de Leeuw
Paul F K Wackers
Wim A Ensink
Martijs J Jonker
Timo M Breit

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We have collected several valuable lessons that will help improve transcriptomics experimentation. These lessons relate to experiment design, execution, and analysis. The cautions, but also the pointers, may help biologists avoid common pitfalls in transcriptomics experimentation and achieve better results with their transcriptome studies.

Indexed as

Gene Expression ProfilingResearch DesignTranscriptomeAnimalsHigh-Throughput Nucleotide SequencingSequence Analysis, RNASoftwareDesign for experimentationexperimental analysisexperimental executionlessons-learnedTranscriptomics

Identifiers

PMID26098945
PMCPMC4581358

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.