ArticleNature genetics2015
Consistent in-frame internal tandem duplications of BCOR characterize clear cell sarcoma of the kidney.
Article in Nature genetics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 76 papers.
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Who cites it
76 citing papers in PubMed, 171 citations in OpenAlex.
- Renal clear cell sarcoma in children: A case report.Biomedical reports · 2026Article
- Marked Anaplasia Obscuring the Diagnosis of Clear Cell Sarcoma of the Kidney in Pretreatment Needle Biopsy.Pathology international · 2026Article
- Data set for reporting paediatric renal tumours: recommendations from the international collaboration on cancer reporting (ICCR).Histopathology · 2025Review
- Paediatric renal tumors: An insight into molecular characteristics, histomorphology and syndromic association.World journal of nephrology · 2025Review
- Development, optimization and application of a universal fluorescence multiplex PCR-based assay to detect BCOR genetic alterations in pediatric tumors.Diagnostic pathology · 2025Article
- Paediatric renal tumours: an update on challenges and recent developments.Virchows Archiv : an international journal of pathology · 2025Review
- Characterization of malignant kidney tumors in childhood byWorld journal of urology · 2024Article
- Functional Classification of Fusion Proteins in Sarcoma.Cancers · 2024Review
- Outcomes of children with clear cell sarcoma of kidney following NWTS strategies in Shanghai China (2003-2021).PloS one · 2024Article
- Article
- High-grade neuroepithelial tumor with EP300::BCOR fusion and negative BCOR immunohistochemical expression: a case report.Brain tumor pathology · 2023Article
- Rare Case of BCOR::CCNB3 Sarcoma of Bone.The American journal of case reports · 2023Article
- Molecular Signature of Biological Aggressiveness in Clear Cell Sarcoma of the Kidney (CCSK).International journal of molecular sciences · 2023Article
- Article
- Ewing and Ewing-like sarcomas: A morphological guide through genetically-defined entities.Pathology international · 2023Review
- Embryonal Tumors of the Central Nervous System with Multilayered Rosettes and Atypical Teratoid/Rhabdoid Tumors.Advances in experimental medicine and biology · 2023Article
- Review
- Small round cell sarcomas.Nature reviews. Disease primers · 2022Review
- Paediatric BCOR-associated sarcomas with a novel long spliced internal tandem duplication of BCOR exon 15.The journal of pathology. Clinical research · 2022Article
- Intra- and extra-cranial BCOR-ITD tumours are separate entities within the BCOR-rearranged family.The journal of pathology. Clinical research · 2022Article
16 more citing papers are in PubMed but not listed here.
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Authors and funding
8 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Clear cell sarcoma of the kidney (CCSK) is one of the major pediatric renal neoplasms, but its associated genetic abnormalities are largely unknown. We identified internal tandem duplications in the BCOR gene (BCL6 corepressor) affecting the C terminus in 100% (20/20) of CCSK tumors but in none (0/193) of the other pediatric renal tumors. CCSK tumors expressed only an aberrant BCOR allele, indicating a close correlation between BCOR aberration and CCSK tumorigenesis.
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