Evidence map›Paper›PMID 26098620›Full record

Observational studyJAMA internal medicine2015

Urinary Incontinence Before and After Bariatric Surgery.

Leslee L Subak, Wendy C King, Steven H Belle, Jia-Yuh Chen, Anita P Courcoulas, Faith E Ebel, David R Flum, Saurabh Khandelwal, John R Pender, Sheila K Pierson and 5 more

Abstract readObservational Study
In one paragraph

Observational study in JAMA internal medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 2 pooled it
9.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 2 syntheses or guidelines pooled it, 114 citations in OpenAlex.

  1. Pooled it
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  8. Observational
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  14. Observational
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  17. Article
  18. Physical Activity, Diet, and Incident Urinary Incontinence in Postmenopausal Women: Women's Health Initiative Observational Study.The journals of gerontology. Series A, Biological sciences and medical sciences · 2021
    Observational
  19. Article
  20. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

15 authors at 8 institutions in 1 country.

Leslee L SubakDepartment of Obstetrics, Gynecology, and Reproductive Sciences, University of California, San Francisco2Department of Epidemiology and Biostatistics, University of California, San Francisco3Department of Urology, University of California, San Francisco4S.
Wendy C KingDepartment of Epidemiology, University of Pittsburgh Graduate School of Public Health, Pittsburgh, Pennsylvania.
Steven H BelleDepartment of Epidemiology, University of Pittsburgh Graduate School of Public Health, Pittsburgh, Pennsylvania6Department of Biostatistics, University of Pittsburgh Graduate School of Public Health, Pittsburgh, Pennsylvania.
Jia-Yuh ChenDepartment of Biostatistics, University of Pittsburgh Graduate School of Public Health, Pittsburgh, Pennsylvania.
Anita P CourcoulasDepartment of Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania.
Faith E EbelGI Metabolic and Bariatric Surgery, Weill Cornell Medical College, New York, New York.
David R FlumDepartment of Surgery, University of Washington, Seattle.
Saurabh KhandelwalDepartment of Surgery, University of Washington, Seattle.
John R PenderDepartment of Surgery, Brody School of Medicine, East Carolina University, Greenville, North Carolina.
Sheila K PiersonDepartment of Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania.
Walter J PoriesDepartment of Surgery, Brody School of Medicine, East Carolina University, Greenville, North Carolina.
Kristine J SteffenDepartment of Neuroscience, Neuropsychiatric Research Institute, University of North Dakota School of Medicine and Health Sciences, Grand Forks.
Gladys W StrainGI Metabolic and Bariatric Surgery, Weill Cornell Medical College, New York, New York.
Bruce M WolfeDepartment of Surgery, Oregon Health & Science University, Portland.
Alison J HuangDepartment of Medicine, University of California, San Francisco.
University of Pittsburgh · USCornell University · USEast Carolina University · USUniversity of California, San Francisco · USUniversity of Pittsburgh Medical Center · USUniversity of Washington · USOregon Health & Science University · USUniversity of North Dakota · US

Funding

UNIVERSITY OF PITTSBURGH CLINICAL AND TRANSLATIONAL SCIENCE INSTITUTE: BPCAUL1RR024153 · NCRR · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI REIS, STEVEN E · 2006 to 2011
$73.9M
University of Pittsburgh Clinical and Translational Science InstituteUL1TR000005 · NCATS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI REIS, STEVEN E · 2012 to 2015
$50.8M
CTSA INFRASTRUCTURE FOR PEDIATRIC RESEARCHUL1RR024996 · NCRR · WEILL MEDICAL COLL OF CORNELL UNIV · PI IMPERATO-MCGINLEY, JULIANNE L · 2007 to 2011
$49.6M
Clinical and Translational Science CenterUL1TR000457 · NCATS · WEILL MEDICAL COLL OF CORNELL UNIV · PI IMPERATO-MCGINLEY, JULIANNE L · 2012 to 2016
$46.0M
ZIPRASIDONE IN NORMAL HEPATIC FUNCTION SUBJECTS &IN HEPATIC DYSFUCTIN SUBJECTSM01RR000037 · NCRR · UNIVERSITY OF WASHINGTON · PI MCDONALD, RUTH C · 1985 to 2007
$33.8M
Continuation of the Longitudinal Assessment of Bariatric Surgery (LABS) - DCCU01DK066557 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BELLE, STEVEN H. · 2003 to 2015
$15.8M
BARIATRIC SURGERY CLINICAL RESEARCH CONSORTIUMU01DK066555 · NIDDK · UNIVERSITY OF CALIFORNIA DAVIS · PI WOLFE, BRUCE M · 2003 to 2013
$6.2M
Effect of Bariatric Surgery on Insulin Resistance &CVDU01DK066585 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI COURCOULAS, ANITA P · 2003 to 2013
$5.0M
Bariatric Surgery: Outcomes & Impact on PathophysiologyU01DK066667 · NIDDK · MOUNT SINAI SCHOOL OF MEDICINE OF NYU · PI BERK, PAUL DAVID, POMP, ALFONS · 2003 to 2015
$4.7M
Longtitudinal Assessment of Bariatric Surgery (LABS)U01DK066568 · NIDDK · UNIVERSITY OF WASHINGTON · PI FLUM, DAVID R · 2003 to 2013
$4.3M
East Carolina University Bariatric Surgery Clinical CenterU01DK066526 · NIDDK · EAST CAROLINA UNIVERSITY · PI PORIES, WALTER JULIUS · 2003 to 2015
$4.0M
Longitudinal Assessment of Bariatric Surgery (LABS)U01DK066471 · NIDDK · SANFORD RESEARCH NORTH · PI MITCHELL, JAMES EDWARD · 2003 to 2015
$3.7M
NCATS NIH HHS UL1 TR000005NCATS NIH HHS UL1 TR000457NCRR NIH HHS M01 RR000037NCRR NIH HHS M01RR-00037NCRR NIH HHS UL1 RR024153NCRR NIH HHS UL1-RR024153NCRR NIH HHS UL1 RR024996NCRR NIH HHS UL1-RR024996NIA NIH HHS K23 AG038335NIDDK NIH HHS K24 DK080775NIDDK NIH HHS U01 DK066471NIDDK NIH HHS U01 DK066526NIDDK NIH HHS U01 DK066555NIDDK NIH HHS U01 DK066557NIDDK NIH HHS U01 DK066568NIDDK NIH HHS U01 DK066585NIDDK NIH HHS U01 DK066667NIDDK NIH HHS U01-DK66471NIDDK NIH HHS U01-DK66526NIDDK NIH HHS U01-DK66555NIDDK NIH HHS U01-DK66568NIDDK NIH HHS U01-DK66585NIDDK NIH HHS U01-DK66667
6 · The paper itself

Abstract

importanceAmong women and men with severe obesity, evidence for improvement in urinary incontinence beyond the first year after bariatric surgery-induced weight loss is lacking.

objectivesTo examine change in urinary incontinence before and after bariatric surgery and to identify factors associated with improvement and remission among women and men in the first 3 years after bariatric surgery. DESIGN, SETTING, AND

participantsThe Longitudinal Assessment of Bariatric Surgery 2 is an observational cohort study at 10 US hospitals in 6 geographically diverse clinical centers. Participants were recruited between February 21, 2005, and February 17, 2009. Adults undergoing first-time bariatric surgical procedures as part of clinical care by participating surgeons between March 14, 2006, and April 24, 2009, were followed up for 3 years (through October 24, 2012).

interventionParticipants undergoing bariatric surgery completed research assessments before the procedure and annually thereafter. MAIN OUTCOMES AND MEASURES: The frequency and type of urinary incontinence episodes in the past 3 months were assessed using a validated questionnaire. Prevalent urinary incontinence was defined as at least weekly urinary incontinence episodes, and remission was defined as change from prevalent urinary incontinence at baseline to less than weekly urinary incontinence episodes at follow-up.

resultsOf 2458 participants, 1987 (80.8%) completed baseline and follow-up assessments. At baseline, the median age was 47 years (age range, 18-78 years), the median body mass index was 46 kg/m2 (range, 34-94 kg/m2), and 1565 of 1987 (78.8%) were women. Urinary incontinence was more prevalent among women (49.3%; 95% CI, 46.9%-51.9%) than men (21.8%; 95% CI, 18.2%-26.1%) (P < .001). After a mean 1-year weight loss of 29.5% (95% CI, 29.0%-30.1%) in women and 27.0% (95% CI, 25.9%-28.6%) in men, year 1 urinary incontinence prevalence was significantly lower among women (18.3%; 95% CI, 16.4%-20.4%) and men (9.8%; 95% CI, 7.2%-13.4%) (P < .001 for all). The 3-year prevalence was higher than the 1-year prevalence for both sexes (24.8%; 95% CI, 21.8%-26.5% among women and 12.2%; 95% CI, 9.0%-16.4% among men) but was substantially lower than baseline (P < .001 for all). Weight loss was independently related to urinary incontinence remission (relative risk, 1.08; 95% CI, 1.06-1.10 in women and 1.07; 95% CI, 1.02-1.13 in men) per 5% weight loss, as were younger age and the absence of a severe walking limitation. CONCLUSIONS AND RELEVANCE: Among women and men with severe obesity, bariatric surgery was associated with substantially reduced urinary incontinence over 3 years. Improvement in urinary incontinence may be an important benefit of bariatric surgery.

Indexed as

Bariatric SurgeryAdolescentAdultAgedAge FactorsBody Mass IndexCohort StudiesComorbidityFemaleHumansLongitudinal StudiesMaleMiddle AgedObesityObesity, MorbidPrevalence

Identifiers

PMID26098620
PMCPMC4529061
OpenAlexW2104189905

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.