ArticlePloS one2015
Transcriptome Analysis to Identify Cold-Responsive Genes in Amur Carp (Cyprinus carpio haematopterus).
Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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15 citing papers in PubMed.
- Genomic Signatures of Adaptive Evolution inInternational journal of molecular sciences · 2025Article
- Muscle Transcriptome Sequencing Revealed Thermal Stress-Responsive Regulatory Genes in Farmed Rohu, Labeo rohita (Hamilton, 1822).Marine biotechnology (New York, N.Y.) · 2023Article
- Climate Adaptation and Drift Shape the Genomes of Two Eel-Goby Sister Species Endemic to Contrasting Latitude.Animals : an open access journal from MDPI · 2023Article
- The adaptive evolution of Leuciscus waleckii in Lake Dali Nur and convergent evolution of Cypriniformes fishes inhabiting extremely alkaline environments.Genome biology and evolution · 2023Article
- Identification of Genes Related to Cold Tolerance and Novel Genetic Markers for Molecular Breeding in Taiwan Tilapia (Animals : an open access journal from MDPI · 2021Article
- Characterization of Biological Pathways Regulating Acute Cold Resistance of Zebrafish.International journal of molecular sciences · 2021Article
- Resequencing and SNP discovery of Amur ide (Leuciscus waleckii) provides insights into local adaptations to extreme environments.Scientific reports · 2021Article
- Cold Acclimation for Enhancing the Cold Tolerance of Zebrafish Cells.Frontiers in physiology · 2021Article
- A new strain group of common carp: The genetic differences and admixture events betweenEcology and evolution · 2020Article
- Transcriptional Programs Underlying Cold Acclimation of Common Carp (Frontiers in genetics · 2020Article
- Transcriptomic evidences of local thermal adaptation for the native fish Colossoma macropomum (Cuvier, 1818).Genetics and molecular biology · 2020Article
- Transcriptome analyses provide the first insight into the molecular basis of cold tolerance in Larimichthys polyactis.Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology · 2020Article
- Network of microRNA-transcriptional factor-mRNA in cold response of turbot Scophthalmus maximus.Fish physiology and biochemistry · 2019Article
- Regional differences in thermal adaptation of a cold-water fish Rhynchocypris oxycephalus revealed by thermal tolerance and transcriptomic responses.Scientific reports · 2018Article
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4 authors.
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Abstract
The adaptation of fish to low temperatures is the result of long-term evolution. Amur carp (Cyprinus carpio haematopterus) survives low temperatures (0-4°C) for six months per year. Therefore, we chose this fish as a model organism to study the mechanisms of cold-adaptive responses using high-throughput sequencing technology. This system provided an excellent model for exploring the relationship between evolutionary genomic changes and environmental adaptations. The Amur carp transcriptome was sequenced using the Illumina platform and was assembled into 163,121 cDNA contigs, with an average read length of 594 bp and an N50 length of 913 bp. A total of 162,339 coding sequences (CDSs) were identified and of 32,730 unique CDSs were annotated. Gene Ontology (GO), EuKaryotic Orthologous Groups (KOG) and Kyoto Encyclopedia of Genes and Genomes (KEGG) analyses were performed to classify all CDSs into different functional categories. A large number of cold-responsive genes were detected in different tissues at different temperatures. A total of 9,427 microsatellites were identified and classified, with 1952 identifying in cold-responsive genes. Based on GO enrichment analysis of the cold-induced genes, "protein localization" and "protein transport" were the most highly represented biological processes. "Circadian rhythm," "protein processing in endoplasmic reticulum," "endocytosis," "insulin signaling pathway," and "lysosome" were the most highly enriched pathways for the genes induced by cold stress. Our data greatly contribute to the common carp (C. carpio) transcriptome resource, and the identification of cold-responsive genes in different tissues at different temperatures will aid in deciphering the genetic basis of ecological and environmental adaptations in this species. Based on our results, the Amur carp has evolved special strategies to survive low temperatures, and these strategies include the system-wide or tissue-specific induction of gene expression during their six-month overwintering period.
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