ArticlePain2015
Deficits in pain perception in borderline personality disorder: results from the thermal grill illusion.
Article in Pain, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
24 citing papers in PubMed, 59 citations in OpenAlex.
- Reliability and Validity of a Novel, Portable Thermal Grill Illusion Apparatus Using Two Graphene Probes: An Initial Psychophysical Validation Study.European journal of pain (London, England) · 2026Observational
- Sensing vs. seeing: body experience rather than mere body observation is linked to efficiency of descending pain modulation.Scientific reports · 2026Article
- RDoC Mechanisms Underlying Bodily Symptoms in Psychiatry: A Scoping Review.Psychology research and behavior management · 2026Review
- Temporal Summation of Pain Unpleasantness Is Increased in Borderline Personality Disorder.European journal of pain (London, England) · 2025Article
- Attenuation of Self-Induced Pain in Women With Nonsuicidal Self-Injury and Healthy Controls.European journal of pain (London, England) · 2025Article
- Pain perception in personality disorders.PloS one · 2025Article
- Pain sensitivity as a state marker and predictor for adolescent non-suicidal self-injury.Psychological medicine · 2024Article
- Acute, Chronic, and Everyday Physical Pain in Borderline Personality Disorder.Current psychiatry reports · 2024Review
- Strong and aversive cold processing and pain facilitation in fibromyalgia patients relates to augmented thermal grill illusion.Scientific reports · 2023Article
- Associations of state or trait dissociation with severity of psychopathology in young people with borderline personality disorder.Borderline personality disorder and emotion dysregulation · 2023Article
- A novel thermoelectric device integrated with a psychophysical paradigm to study pain processing in human subjects.Journal of neuroscience methods · 2023Article
- Thermal illusions for thermal displays: a review.Frontiers in human neuroscience · 2023Review
- Thermal Grill Illusion in Chronic Lower Back Pain: A Case-Control Study.Journal of pain research · 2023Article
- Superior temporal gyrus and cerebellar loops predict nonsuicidal self-injury in major depressive disorder patients by multimodal neuroimaging.Translational psychiatry · 2022Article
- A systematic scoping review of dissociation in borderline personality disorder and implications for research and clinical practice: Exploring the fog.The Australian and New Zealand journal of psychiatry · 2022Article
- Augmented pain inhibition and higher integration of pain modulatory brain networks in women with self-injury behavior.Molecular psychiatry · 2022Article
- A Theoretical Endogenous Opioid Neurobiological Framework for Co-occurring Pain, Trauma, and Non-suicidal Self-injury.Current pain and headache reports · 2022Review
- Pleasant touch perception in borderline personality disorder and its relationship with disturbed body representation.Borderline personality disorder and emotion dysregulation · 2022Article
- Advancing a temporal framework for understanding the biology of nonsuicidal self- injury: An expert review.Neuroscience and biobehavioral reviews · 2021Review
- A Review on Various Topics on the Thermal Grill Illusion.Journal of clinical medicine · 2021Review
Corrections and comments
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Authors and funding
8 authors at 5 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
It is well documented that borderline personality disorder (BPD) is characterized by reduced pain sensitivity, which might be related to nonsuicidal self-injury and dissociative experiences in patients with BPD. However, it remains an open question whether this insensitivity relies at least partly on altered sensory integration or on an altered evaluation of pain or a combination of both. In this study, we used the thermal grill illusion (TGI), describing a painful sensation induced by the application of alternating cold and warm nonnoxious stimuli, in patients with either current or remitted BPD as well as matched healthy controls. Two additional conditions, applying warm or cold temperatures only, served as control. We further assessed thermal perception, discrimination, and pain thresholds. We found significantly reduced heat and cold pain thresholds for the current BPD group, as well as reduced cold pain thresholds for the remitted BPD group, as compared with the HC group. Current BPD patients perceived a less-intense TGI in terms of induced pain and unpleasantness, while their general ability to perceive this kind of illusion seemed to be unaffected. Thermal grill illusion magnitude was negatively correlated with dissociation and traumatization only in the current BPD patients. These results indicate that higher-order pain perception is altered in current BPD, which seems to normalize after remission. We discuss these findings against the background of neurophysiological evidence for the TGI in general and reduced pain sensitivity in BPD and suggest a relationship to alterations in N-methyl-D-aspartate neurotransmission.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.