ArticleThe Journal of head trauma rehabilitation
Association Between Traumatic Brain Injury-Related Brain Lesions and Long-term Caregiver Burden.
Article in The Journal of head trauma rehabilitation. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Using Implementation Science to Improve Health Care Access and Quality for People With Traumatic Brain Injury-Related Morbidity (I-HEAL): Protocol for a Translational Multiproject Program Award.JMIR research protocols · 2026Article
- Patient-centered burdens and economic outcomes among patients who are veterans, people with intellectual and developmental disabilities, and people living in rural areas and their caregivers: a scoping review.Frontiers in public health · 2026Article
- Beneficial Effects of Human Schwann Cell-Derived Exosomes in Mitigating Secondary Damage After Penetrating Ballistic-Like Brain Injury.Journal of neurotrauma · 2024Article
- The burden of traumatic brain injury on caregivers: exploring the predictive factors in a multi-centric study.BMC psychology · 2024Article
- Factors associated with psychological distress in caregivers of patients with malignant gliomas.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022Article
- Neurofeedback in patients with frontal brain lesions: A randomized, controlled double-blind trial.Frontiers in human neuroscience · 2022Article
- Article
- Religious Coping in Caregiver of Patients with Acquired Brain Injuries.Journal of religion and health · 2019Article
- Theory of Mind Impairments Highlighted With an Ecological Performance-Based Test Indicate Behavioral Executive Deficits in Traumatic Brain Injury.Frontiers in neurology · 2019Article
- Evaluating Patient Brain and Behavior Pathways to Caregiver Health in Neurodegenerative Diseases.Dementia and geriatric cognitive disorders · 2019Article
- Amelioration of Penetrating Ballistic-Like Brain Injury Induced Cognitive Deficits after Neuronal Differentiation of Transplanted Human Neural Stem Cells.Journal of neurotrauma · 2017Article
- Assessment of the consequences of caregiving in psychosis: a psychometric comparison of the Zarit Burden Interview (ZBI) and the Involvement Evaluation Questionnaire (IEQ).Health and quality of life outcomes · 2017Article
- Quality of life after brain injury (QOLIBRI): Italian validation of the proxy version.Internal and emergency medicine · 2017Article
- Understanding the Associations between Caregiver Characteristics and Cognitive Function of Adults with Cancer: A Scoping Review.Asia-Pacific journal of oncology nursingArticle
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
objectiveTo investigate the association between traumatic brain injury (TBI)-related brain lesions and long-term caregiver burden in relation to dysexecutive syndrome.
settingNational Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland.
participantsA total of 256 participants: 105 combat veterans with TBI, 23 healthy control combat veterans (HCv), and 128 caregivers. OUTCOME MEASURE: Caregiver burden assessed by the Zarit Burden Interview at 40 years postinjury.
designParticipants with penetrating TBI were compared with HCv on perceived caregiver burden and neuropsychological assessment measures. Data of computed tomographic scans (overlay lesion maps of participants with a penetrating TBI whose caregivers have a significantly high burden) and behavioral statistical analyses were combined to identify brain lesions associated with caregiver burden.
resultsBurden was greater in caregivers of veterans with TBI than in caregivers of HCv. Caregivers of participants with lesions affecting cognitive and behavioral indicators of dysexecutive syndrome (ie, left dorsolateral prefrontal cortex and dorsal anterior cingulate cortex) showed greater long-term burden than caregivers of participants with lesions elsewhere in the brain. CONCLUSION AND IMPLICATION: The TBI-related brain lesions have a lasting effect on long-term caregiver burden due to cognitive and behavioral factors associated with dysexecutive syndrome.
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