Evidence map›Paper›PMID 26097893›Full record

ArticleAddictive behaviors reports2015

Impact of binge alcohol on mortality among people who inject drugs.

Cheyenne Johnson, Huiru Dong, Keith Ahamad, Kanna Hayashi, M J Milloy, Thomas Kerr, Evan Wood

Abstract read
In one paragraph

Article in Addictive behaviors reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Article
  7. Alcohol Use among Persons on Methadone Treatment.Addictive disorders & their treatment · 2017
    Article
  8. Observational
  9. Article
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Cheyenne JohnsonBritish Columbia Centre for Excellence in HIV/AIDS, St. Paul's Hospital 603-1081 Burrard Street, Vancouver, British Columbia, Canada V6Z 1Y6.
Huiru DongBritish Columbia Centre for Excellence in HIV/AIDS, St. Paul's Hospital 603-1081 Burrard Street, Vancouver, British Columbia, Canada V6Z 1Y6.
Keith AhamadBritish Columbia Centre for Excellence in HIV/AIDS, St. Paul's Hospital 603-1081 Burrard Street, Vancouver, British Columbia, Canada V6Z 1Y6 ; Department of Family Practice, University of British Columbia.
Kanna HayashiBritish Columbia Centre for Excellence in HIV/AIDS, St. Paul's Hospital 603-1081 Burrard Street, Vancouver, British Columbia, Canada V6Z 1Y6 ; Department of Medicine, University of British Columbia.
M J MilloyBritish Columbia Centre for Excellence in HIV/AIDS, St. Paul's Hospital 603-1081 Burrard Street, Vancouver, British Columbia, Canada V6Z 1Y6 ; Department of Medicine, University of British Columbia.
Thomas KerrBritish Columbia Centre for Excellence in HIV/AIDS, St. Paul's Hospital 603-1081 Burrard Street, Vancouver, British Columbia, Canada V6Z 1Y6 ; Department of Medicine, University of British Columbia.
Evan WoodBritish Columbia Centre for Excellence in HIV/AIDS, St. Paul's Hospital 603-1081 Burrard Street, Vancouver, British Columbia, Canada V6Z 1Y6 ; Department of Medicine, University of British Columbia.

Funding

Vancouver Drug Users Study: The Impacts of Evolving Drug Use Patterns on HIV/AIDSU01DA038886 · NIDA · UNIVERSITY OF BRITISH COLUMBIA · PI DEBECK, KORA, HAYASHI, KANNA · 2015 to 2024
$12.1M
SYRINGE ACCESS AND RISK FACTORS ON HIV TRANSMISSIONR01DA011591 · NIDA · UNIVERSITY OF BRITISH COLUMBIA · PI KERR, THOMAS · 1998 to 2014
$5.9M
Impacts of universal access to HIV/AIDS care among HIV+ injection drug usersR01DA021525 · NIDA · UNIVERSITY OF BRITISH COLUMBIA · PI MILLOY, M-J · 2007 to 2016
$5.8M
Mentoring the next generation of addiction clinician scientists while responding to the opioid epidemicR25DA037756 · NIDA · UNIVERSITY OF BRITISH COLUMBIA · PI FAIRBAIRN, NADIA · 2014 to 2023
$3.6M
NIDA NIH HHS R01 DA011591NIDA NIH HHS R01 DA021525NIDA NIH HHS R25 DA037756NIDA NIH HHS U01 DA038886
6 · The paper itself

Abstract

introductionWhile the impacts of illicit drug use on mortality have been well described, the impact of poly-substance that includes alcohol has received less attention. We examined the impact of binge alcohol use on mortality among a cohort of people who inject drugs (PWID) in a Canadian setting.

methodsUsing data derived from a prospective cohort study of PWID in Vancouver, Canada recruited between May 1996 and November 2013. We ascertained dates and causes of death through a confidential linkage with the provincial registry and examined the impact of binge alcohol use. The primary outcome of interest was all-cause mortality. We used Cox proportional hazard regression to determine factors associated with mortality, including socio-demographic characteristics, drug use patterns and other risk behaviours.

resultsDuring the study period, 2550 individuals were followed (844 of whom were HIV positive at baseline) for a median of 75.4 months (interquartile range 37.9 113.2). Of these, 795 (31%) participants reported binge alcohol use at some time during the study period. In multivariable analyses, binge alcohol use remained independently associated with all-cause-mortality (adjusted hazard ratio=1.41; 95% confidence interval: 1.06-1.88) after adjustment for other drug use patterns.

conclusionsBinge alcohol use was associated with time to all-cause mortality among PWID in this setting. Since alcohol use is often overlooked as a risk factor for mortality among this population, these findings highlight the continued need to incorporate addiction treatment and public health interventions and policies that address binge alcohol use to reduce alcohol related-harms.

Indexed as

alcoholbinge alcoholillicit drug usemortalitypeople who inject drugs (PWID)Vancouver

Identifiers

PMID26097893
PMCPMC4470370

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.