Evidence map›Paper›PMID 26097514›Full record

ArticlePolymer chemistry2015

Well-defined single polymer nanoparticles for the antibody-targeted delivery of chemotherapeutic agents.

D D Lane, D Y Chiu, F Y Su, S Srinivasan, H B Kern, O W Press, P S Stayton, A J Convertine

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Polymer chemistry, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Polymer nanostructures synthesized by controlled living polymerization for tumor-targeted drug delivery.Journal of controlled release : official journal of the Controlled Release Society · 2015
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

D D LaneMolecular Engineering and Sciences Institute, Department of Bioengineering, Box 355061, Seattle, WA, 98195, USA.
D Y ChiuMolecular Engineering and Sciences Institute, Department of Bioengineering, Box 355061, Seattle, WA, 98195, USA.
F Y SuMolecular Engineering and Sciences Institute, Department of Bioengineering, Box 355061, Seattle, WA, 98195, USA.
S SrinivasanMolecular Engineering and Sciences Institute, Department of Bioengineering, Box 355061, Seattle, WA, 98195, USA.
H B KernMolecular Engineering and Sciences Institute, Department of Bioengineering, Box 355061, Seattle, WA, 98195, USA.
O W PressMolecular Engineering and Sciences Institute, Department of Bioengineering, Box 355061, Seattle, WA, 98195, USA.
P S StaytonMolecular Engineering and Sciences Institute, Department of Bioengineering, Box 355061, Seattle, WA, 98195, USA.
A J ConvertineMolecular Engineering and Sciences Institute, Department of Bioengineering, Box 355061, Seattle, WA, 98195, USA.

Funding

University of Washington Medical Scientist Training Program: MD/PhDT32GM007266 · NIGMS · UNIVERSITY OF WASHINGTON · PI HORWITZ, MARSHALL S. · 1985 to 2023
$30.4M
Biofunctional Polymers for Intracellular Drug DeliveryR01EB002991 · NIBIB · UNIVERSITY OF WASHINGTON · PI STAYTON, PATRICK S. · 2003 to 2011
$3.9M
Intracellular delivery of proapoptotic peptide drugs for the treatment of cancerR21EB014572 · NIBIB · UNIVERSITY OF WASHINGTON · PI STAYTON, PATRICK S. · 2012 to 2013
$450k
NIBIB NIH HHS R01 EB002991NIBIB NIH HHS R21 EB014572NIGMS NIH HHS T32 GM007266
6 · The paper itself

Abstract

Aqueous reversible addition-fragmentation chain transfer (RAFT) polymerization was employed to prepare a series of linear copolymers of N,N-dimethylacrylamide (DMA) and 2-hydroxyethylacrylamide (HEAm) with narrow Đ values over a molecular weight range spanning three orders of magnitude (10

Identifiers

PMID26097514
PMCPMC4470501

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.