Evidence map›Paper›PMID 26097445›Full record

ArticleAdvanced functional materials2015

Cationic Polymer Modified Mesoporous Silica Nanoparticles for Targeted SiRNA Delivery to HER2+ Breast Cancer.

Worapol Ngamcherdtrakul, Jingga Morry, Shenda Gu, David J Castro, Shaun M Goodyear, Thanapon Sangvanich, Moataz M Reda, Richard Lee, Samuel A Mihelic, Brandon L Beckman and 3 more

Open access · greenAbstract read
In one paragraph

Article in Advanced functional materials, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers.

0numbers the graph read from it
0cells of the map it votes in
63citing papers in PubMed
10.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

63 citing papers in PubMed, 188 citations in OpenAlex.

  1. Exploring tyrosine kinase inhibitors for HER2-positive breast cancer: comprehensive review on a complete pharmacology-molecular mechanisms, safety profiles, and insights from preclinical and clinical studies.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
    Review
  2. Article
  3. Review
  4. Review
  5. Review
  6. Article
  7. Review
  8. Review
  9. Non-Coding RNAs in Breast Cancer: Diagnostic and Therapeutic Implications.International journal of molecular sciences · 2024
    Review
  10. Nanotechnology Applications in Breast Cancer Immunotherapy.Small (Weinheim an der Bergstrasse, Germany) · 2024
    Review
  11. Review
  12. Review
  13. The landscape of nanoparticle-based siRNA delivery and therapeutic development.Molecular therapy : the journal of the American Society of Gene Therapy · 2024
    Review
  14. Review
  15. Nanomedicine in cancer therapy.Signal transduction and targeted therapy · 2023
    Review
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article

3 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Worapol NgamcherdtrakulDepartment of Biomedical Engineering, Oregon Health & Science University 3303 SW Bond Ave, Portland, OR 97239.
Jingga MorryDepartment of Biomedical Engineering, Oregon Health & Science University 3303 SW Bond Ave, Portland, OR 97239.
Shenda GuDepartment of Biomedical Engineering, Oregon Health & Science University 3303 SW Bond Ave, Portland, OR 97239.
David J CastroDepartment of Biomedical Engineering, Oregon Health & Science University 3303 SW Bond Ave, Portland, OR 97239.
Shaun M GoodyearDepartment of Biomedical Engineering, Oregon Health & Science University 3303 SW Bond Ave, Portland, OR 97239.
Thanapon SangvanichDepartment of Biomedical Engineering, Oregon Health & Science University 3303 SW Bond Ave, Portland, OR 97239.
Moataz M RedaDepartment of Biomedical Engineering, Oregon Health & Science University 3303 SW Bond Ave, Portland, OR 97239.
Richard LeeDepartment of Biomedical Engineering, Oregon Health & Science University 3303 SW Bond Ave, Portland, OR 97239.
Samuel A MihelicDepartment of Biomedical Engineering, Oregon Health & Science University 3303 SW Bond Ave, Portland, OR 97239.
Brandon L BeckmanDepartment of Biomedical Engineering, Oregon Health & Science University 3303 SW Bond Ave, Portland, OR 97239.
Zhi HuDepartment of Biomedical Engineering, Oregon Health & Science University 3303 SW Bond Ave, Portland, OR 97239.
Joe W GrayDepartment of Biomedical Engineering, Oregon Health & Science University 3303 SW Bond Ave, Portland, OR 97239.
Wassana YantaseeDepartment of Biomedical Engineering, Oregon Health & Science University 3303 SW Bond Ave, Portland, OR 97239.
Oregon Health & Science University · USPDX Pharmaceuticals (United States) · US

Funding

Systems-Based Predictions of Responses to Cancer TherapyU54CA112970 · NCI · UNIVERSITY OF CALIF-LAWRENC BERKELEY LAB · PI SPELLMAN, PAUL T. · 2004 to 2014
$27.1M
Nephrogenic Systemic Fibrosis (NSF): A Rodent Model for Therapeutic InterventionR01GM089918 · NIGMS · OREGON HEALTH & SCIENCE UNIVERSITY · PI YANTASEE, WASSANA · 2010 to 2013
$1.8M
Iron functionalized silica as oral phosphate binder to treat hyperphosphatemiaR41DK094571 · NIDDK · PDX PHARMACEUTICALS, INC. · PI YANTASEE, WASSANA · 2012 to 2012
$300k
NCI NIH HHS HHSN261201300078CNCI NIH HHS U54 CA112970NIDDK NIH HHS R41 DK094571NIGMS NIH HHS R01 GM089918
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

cancer nanomedicineHER2+ breast cancermesoporous silica nanoparticlessiRNA

Identifiers

PMID26097445
PMCPMC4469082
OpenAlexW2044626782

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.