Evidence map›Paper›PMID 26096866›Full record

ReviewIndian journal of pediatrics2016

Bone and Joint Infections in Children: Acute Hematogenous Osteomyelitis.

Anil Agarwal, Aditya N Aggarwal

Abstract readReview
PubMed Publisher
In one paragraph

Review in Indian journal of pediatrics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
5.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 62 citations in OpenAlex.

  1. Pooled it
  2. Neonatal Osteomyelitis Caused byChildren (Basel, Switzerland) · 2026
    Review
  3. Article
  4. Article
  5. Phage therapeutics: from promises to practices and prospectives.Applied microbiology and biotechnology · 2021
    Review
  6. A Rare Presentation of Brodie Abscess in the Clavicle.Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews · 2021
    Article
  7. Article
  8. Sonography of musculoskeletal infection in children.Ultrasound (Leeds, England) · 2020
    Review
  9. Hip Pain in Children.Deutsches Arzteblatt international · 2020
    Review
  10. Article
  11. Procalcitonin and Pancreatic Stone Protein Function as Biomarkers in Early Diagnosis of Pediatric Acute Osteomyelitis.Medical science monitor : international medical journal of experimental and clinical research · 2017
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Anil AgarwalDepartment of Pediatric Orthopedics, Chacha Nehru Bal Chikitsalaya, Geeta Colony, Delhi, India. rachna_anila@yahoo.co.in.
Aditya N AggarwalDepartment of Orthopedics, UCMS and GTB Hospital, Shahdara, Delhi, India.
Chacha Nehru Bal Chikitsalaya · INGuru Teg Bahadur Hospital · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acute hematogenous osteomyelitis (AHO) is one of the commonest bone infection in childhood. Staphylococcus aureus is the commonest organism causing AHO. With use of advanced diagnostic methods, fastidious Kingella kingae is increasingly becoming an important organism in etiology of osteoarticular infections in children under the age of 3 y. The diagnosis of AHO is primarily clinical. The main clinical symptom and sign in AHO is pain and tenderness over the affected bone especially in the metaphyseal region. However, in a neonate the clinical presentation may be subtle and misleading. Laboratory and radiological investigations supplement the clinical findings. The acute phase reactants such as C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR) are frequently elevated. Ultrasonography and MRI are key imaging modalities for early detection of AHO. Determination of infecting organism in AHO is the key to the correct antibiotic choice, treatment duration and overall management and therefore, organism isolation using blood cultures and site aspiration should be attempted. Several effective antibiotics regimes are available for managing AHO in children. The choice of antibiotic and its duration and mode of delivery requires individualization depending upon severity of infection, causative organism, regional sensitivity patterns, time elapsed between onset of symptoms and child's presentation and the clinical and laboratory response to the treatment. If pus has been evidenced in the soft tissues or bone region, surgical decompression of abscess is mandatory.

Indexed as

OsteomyelitisAcute DiseaseAnti-Bacterial AgentsArthritis, InfectiousChildHumansInfantRetrospective StudiesStaphylococcal InfectionsStaphylococcus aureusAnti-Bacterial AgentsAcute hematogenous osteomyelitisBone and joint infectionsOsteoarticular infectionsOsteomyelitisSeptic arthritis

Identifiers

PMID26096866
OpenAlexW798966580

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.