ArticleDrug and alcohol dependence2015
Genetic overlap between alcohol use disorder and bulimic behaviors in European American and African American women.
Article in Drug and alcohol dependence, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
12 citing papers in PubMed, 25 citations in OpenAlex.
- Cross-Sensitization between Binge Eating and Binge Drinking in a Novel C57BL/6NJ Murine Model of Disease Comorbidity Requires PDE4B Activation.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- A longitudinal test of problematic alcohol use and binge eating among college women: The moderating role of shame.Alcohol (Fayetteville, N.Y.) · 2024Article
- Differential genetic associations between dimensions of eating disorders and alcohol involvement in late adolescent twins.Alcohol, clinical & experimental research · 2023Article
- Binge eating and alcohol consumption: an integrative review.Eating and weight disorders : EWD · 2021Review
- Shared genetic risk between eating disorder- and substance-use-related phenotypes: Evidence from genome-wide association studies.Addiction biology · 2021Article
- Impulsivity and anxiety-related dimensions in adults with bulimic-spectrum disorders differentially relate to eating disordered behaviors.Eating behaviors · 2020Article
- Associations Between Alcohol Involvement and Drive for Thinness and Body Dissatisfaction in Adolescent Twins: A Bivariate Twin Study.Alcoholism, clinical and experimental research · 2018Article
- Illicit Drug Use, Cigarette Smoking, and Eating Disorder Symptoms: Associations in an Adolescent Twin Sample.Journal of studies on alcohol and drugs · 2018Article
- Shared familial risk between bulimic symptoms and alcohol involvement during adolescence.Journal of abnormal psychology · 2017Article
- Genetic epidemiology of eating disorders.Current opinion in psychiatry · 2016Review
- Genetic and environmental components to self-induced vomiting.The International journal of eating disorders · 2016Article
- A Primer on the Genetics of Comorbid Eating Disorders and Substance Use Disorders.European eating disorders review : the journal of the Eating Disorders Association · 2016Review
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundDespite substantial evidence that alcohol use disorder (AUD) and bulimic behaviors (i.e., binge eating and compensatory behaviors) co-occur, insufficient information exists regarding a possible shared etiology. Moreover, although numerous twin studies of European ancestry individuals have reported moderate heritability estimates for AUD and bulimic behaviors, with little evidence for shared environmental factors, research on genetic and environmental risk in African American (AA) individuals is lacking.
methodsWe investigated specific and overlapping genetic and environmental influences on AUD and bulimic behaviors in 3232 European American (EA; 55.38% monozygotic) and 549 AA (42.81% monozygotic) young adult female twins from the Missouri Adolescent Female Twin Study (age range=18-29 years). A structured clinical interview assessed lifetime DSM-5 AUD (minus craving) and bulimic behaviors. Biometrical twin modeling was conducted to generate age-adjusted estimates of genetic and environmental influences on AUD, bulimic behaviors, and their comorbidity.
resultsEstimates of genetic and environmental contributions on AUD and bulimic behaviors could be equated across EA and AA women. Additive genetic effects accounted for 59% (95% CI: 50%, 66%) and 43% (33%, 52%) of the variance in AUD and bulimic behaviors, respectively, with the remainder due to non-shared environmental effects. Shared genetic factors (rg=.33 (.18, .49)) were solely responsible for the correlation between phenotypes; the non-shared environmental correlation was not significant (re=.10 (-.05, .25)).
conclusionsFindings indicate similar magnitudes of genetic and environmental effects on AUD and bulimic behaviors for EA and AA women and implicate common genetic mechanisms underlying liability to these problem behaviors.
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