Evidence map›Paper›PMID 26096474›Full record

Trial reportThe spine journal : official journal of the North American Spine Society2015

Randomized clinical trial assessing whether additional massage treatments for chronic neck pain improve 12- and 26-week outcomes.

Andrea J Cook, Robert D Wellman, Daniel C Cherkin, Janet R Kahn, Karen J Sherman

2 registry-linked trialsAbstract readRandomized Controlled Trial
In one paragraph

Trial report in The spine journal : official journal of the North American Spine Society, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
3.4field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03184220 nacompletednot on this mapstarted 2017, after this paper: background citation

Treatment of Cervical Syndrome With Myofascial Therapies

TypeinterventionalSponsorUniversity of CadizRan2017 to 2018Enrolled54ConditionsCervical SyndromeArmsPhysiotherapy treatment
NCT03322683 nacompletednot on this mapstarted 2018, after this paper: background citation

Vacuum Myofascial Therapy Device for Non-specific Neck Pain. A Single Blind Randomized Clinical Trial

TypeinterventionalSponsorUniversity of CadizRan2018 to 2018Enrolled38ConditionsCervical SyndromeArmsPhysiotherapy treatment with physium device., Conventional physiotherapy treatmen
3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

  1. Massage for neck pain.The Cochrane database of systematic reviews · 2024
    Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Clinical Evidence of Chinese Massage Therapy (Evidence-based complementary and alternative medicine : eCAM · 2017
    Review
  7. Review
  8. Article
  9. Scanning the Global Literature.Global advances in health and medicine · 2015
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Andrea J CookGroup Health Research Institute, 1730 Minor Ave, Suite 1600, Seattle, WA 98101, USA; Department of Biostatistics, University of Washington, 1959 NE Pacific Street, Health Sciences Building F-600, Box 357232, Seattle, WA 98195, USA. Electronic address: cook.aj@ghc.org.
Robert D WellmanGroup Health Research Institute, 1730 Minor Ave, Suite 1600, Seattle, WA 98101, USA.
Daniel C CherkinGroup Health Research Institute, 1730 Minor Ave, Suite 1600, Seattle, WA 98101, USA.
Janet R KahnDepartment of Psychiatry, University of Vermont College of Medicine, 1 South Prospect Street, MS 446AR6, Burlington, VT 05401, USA.
Karen J ShermanGroup Health Research Institute, 1730 Minor Ave, Suite 1600, Seattle, WA 98101, USA; Department of Epidemiology, University of Washington, 1959 NE Pacific Street, Health Sciences Building F-250, Box 357236, Seattle, WA 98195, USA.
Kaiser Permanente Washington Health Research Institute · USSeattle Pacific University · USUniversity of Vermont · US

Funding

Dosing Study of Massage for Neck PainR01AT004411 · NCCIH · KAISER FOUNDATION HEALTH PLAN OF WASHINGTON · PI SHERMAN, KAREN J · 2009 to 2012
$2.5M
NCCIH NIH HHS R01 AT004411
6 · The paper itself

Abstract

background contextThis is the first study to systematically evaluate the value of a longer treatment period for massage. We provide a framework of how to conceptualize an optimal dose in this challenging setting of nonpharmacologic treatments. PURPOSE: The aim was to determine the optimal dose of massage for neck pain. STUDY DESIGN/

settingTwo-phase randomized trial for persons with chronic nonspecific neck pain. Primary randomization to one of five groups receiving 4 weeks of massage (30 minutes 2x/or 3x/wk or 60 minutes 1x, 2x, or 3x/wk). Booster randomization of participants to receive an additional six massages, 60 minutes 1x/wk, or no additional massage. PATIENT SAMPLE: A total of 179 participants from Group Health and the general population of Seattle, WA, USA recruited between June 2010 and August 2011 were included. OUTCOME MEASURES: Primary outcomes self-reported neck-related dysfunction (Neck Disability Index) and pain (0-10 scale) were assessed at baseline, 12, and 26 weeks. Clinically meaningful improvement was defined as greater than or equal to 5-point decrease in dysfunction and greater than or equal to 30% decrease in pain from baseline.

methodsClinically meaningful improvement for each primary outcome with both follow-up times was analyzed using adjusted modified Poisson generalized estimating equations (GEEs). Secondary analyses for the continuous outcomes used linear GEEs.

resultsThere were no observed differences by primary treatment group at 12 or 26 weeks. Those receiving booster dose had improvements in both dysfunction and pain at 12 weeks (dysfunction: relative risk [RR]=1.56 [1.08-2.25], p=.018; pain: RR=1.25 [0.98-1.61], p=.077), but those were nonsignificant at 26 weeks (dysfunction: RR=1.22 [0.85-1.74]; pain: RR=1.09 [0.82-1.43]). Subgroup analysis by primary and booster treatments found the booster dose only effective among those initially randomized to one of the 60-minute massage groups.

conclusions"Booster" doses for those initially receiving 60 minutes of massage should be incorporated into future trials of massage for chronic neck pain.

Indexed as

MassageAdultChronic PainFemaleHumansMaleMiddle AgedNeck PainChronic neck painClinical trial methodsComplementary medicineDosingMassageRandomized clinical trial

Identifiers

PMID26096474
PMCPMC4596391
OpenAlexW1822802202

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.