Evidence map›Paper›PMID 26096189›Full record

ArticleAnnals of epidemiology2015

Sunburn, sun exposure, and sun sensitivity in the Study of Nevi in Children.

Jaya M Satagopan, Susan A Oliveria, Arshi Arora, Michael A Marchetti, Irene Orlow, Stephen W Dusza, Martin A Weinstock, Alon Scope, Alan C Geller, Ashfaq A Marghoob and 1 more

Abstract readEvaluation Study
In one paragraph

Article in Annals of epidemiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Jaya M SatagopanDepartment of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY. Electronic address: satagopj@mskcc.org.
Susan A OliveriaDepartment of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY; Dermatology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY.
Arshi AroraDepartment of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY.
Michael A MarchettiDermatology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY.
Irene OrlowDepartment of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY.
Stephen W DuszaDermatology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY.
Martin A WeinstockDermatoepidemiology Unit, VA Medical Center, Providence, RI; Department of Dermatology, Rhode Island Hospital, Providence, RI; Department of Dermatology, Brown University, Providence, RI; Department of Epidemiology, Brown University, Providence, RI.
Alon ScopeDermatology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY; Department of Dermatology, Sheba Medical Center and Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.
Alan C GellerDepartment of Social and Behavioral Sciences, Harvard School of Public Health, Boston, MA.
Ashfaq A MarghoobDermatology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY.
Allan C HalpernDermatology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY.
Memorial Sloan Kettering Cancer Center · USHarvard University · USProvidence VA Medical Center · USSheba Medical Center · IL

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4M
Clinical and Translational Science CenterUL1TR000457 · NCATS · WEILL MEDICAL COLL OF CORNELL UNIV · PI IMPERATO-MCGINLEY, JULIANNE L · 2012 to 2016
$46.0M
THE FRAMINGHAM SCHOOL STUDY OF NEVI IN CHILDREN SONIC IIR01AR049342 · NIAMS · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI HALPERN, ALLAN C · 2003 to 2013
$6.6M
STUDY OF EXPOSURES, BEHAVIORS, AND BIOMARKERS IN CANCER EPIDEMIOLOGYR01CA137420 · NCI · SLOAN-KETTERING INST CAN RESEARCH · PI SATAGOPAN, JAYA M · 2009 to 2012
$1.6M
NCATS NIH HHS UL1 TR000457NCI NIH HHS P30 CA008748NCI NIH HHS R01 CA137420NIAMS NIH HHS R01 AR049342
6 · The paper itself

Abstract

purposeTo examine the joint effect of sun exposure and sunburn on nevus counts (on the natural logarithm scale; log nevi) and the role of sun sensitivity.

methodsWe describe an analysis of cross-sectional data from 443 children enrolled in the prospective Study of Nevi in Children. To evaluate the joint effect, we partitioned the sum of squares because of interaction between sunburn and sun exposure into orthogonal components representing (1) monotonic increase in log nevi with increasing sun exposure (rate of increase of log nevi depends on sunburn), and (2) nonmonotonic pattern.

resultsIn unadjusted analyses, there was a marginally significant monotonic pattern of interaction (P = .08). In adjusted analyses, sun exposure was associated with higher log nevi among those without sunburn (P < .001), but not among those with sunburn (P = .14). Sunburn was independently associated with log nevi (P = .02), even though sun sensitivity explained 29% (95% confidence interval: 2%-56%, P = .04) of its effect. Children with high sun sensitivity and sunburn had more nevi, regardless of sun exposure.

conclusionsA program of increasing sun protection in early childhood as a strategy for reducing nevi, when applied to the general population, may not equally benefit everyone.

Indexed as

NevusSunlightChildChild, PreschoolCross-Sectional StudiesFemaleHumansMaleMassachusettsProspective StudiesRegression AnalysisRisk FactorsSkin NeoplasmsSunburnSurveys and QuestionnairesUltraviolet RaysProportion of effect explainedRegressionStatistical interactionSun protectionUltraviolet radiation

Identifiers

PMID26096189
PMCPMC4609579
OpenAlexW2160913166

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.