ArticleNature communications2015
Peptidyl-prolyl isomerization targets rice Aux/IAAs for proteasomal degradation during auxin signalling.
Article in Nature communications, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers.
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Who cites it
57 citing papers in PubMed, 120 citations in OpenAlex.
- The SPL transcription factor OsSPL10 regulates rice tillering through auxin signaling to maintain grain yield under drought stress.Plant communications · 2026Article
- An auxin response factor regulates tiller angle and shoot gravitropism by directly activating related gene expression in rice.Journal of advanced research · 2025Article
- The involvement of auxin response factor OsARF7 in positively regulating root development by mediating the expression of OsCRL1 in rice (Oryza sativa L.).Plant molecular biology · 2025Article
- Cotton Bollworm (H. armigera) Effector PPI5 Targets FKBP17-2 to Inhibit ER Immunity and JA/SA Responses, Enhancing Insect Feeding.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Article
- Fine mapping of a major QTL, qECQ8, for rice taste quality.BMC plant biology · 2024Article
- Genetically Encoded, Noise-Tolerant, Auxin Biosensors in Yeast.ACS synthetic biology · 2024Article
- Blocking of amino acid transporter OsAAP7 promoted tillering and yield by determining basic and neutral amino acids accumulation in rice.BMC plant biology · 2024Article
- Switching action modes of miR408-5p mediates auxin signaling in rice.Nature communications · 2024Article
- Proteomics Analysis Reveals the Underlying Factors of Mucilage Disappearance inFoods (Basel, Switzerland) · 2024Article
- Enigmatic role of auxin response factors in plant growth and stress tolerance.Frontiers in plant science · 2024Review
- Nuclear translocation of OsMADS25 facilitated by OsNAR2.1 in reponse to nitrate signals promotes rice root growth by targeting OsMADS27 and OsARF7.Plant communications · 2023Article
- A New Function ofPlants (Basel, Switzerland) · 2023Article
- Nitric oxide-mediated S-nitrosylation of IAA17 protein in intrinsically disordered region represses auxin signaling.Journal of genetics and genomics = Yi chuan xue bao · 2023Article
- Genome-wide identification of Aux/IAA and ARF gene families reveal their potential roles in flower opening of Dendrobium officinale.BMC genomics · 2023Article
- Ubiquitin-Conjugating Enzyme OsUBC11 Affects the Development of Roots via Auxin Pathway.Rice (New York, N.Y.) · 2023Article
- Intrinsic and extrinsic regulators of Aux/IAA protein degradation dynamics.Trends in biochemical sciences · 2022Review
- Root system architecture in rice: impacts of genes, phytohormones and root microbiota.3 Biotech · 2022Review
- Regulation of AUXIN RESPONSE FACTOR condensation and nucleo-cytoplasmic partitioning.Nature communications · 2022Article
- The histone deacetylase 1/GSK3/SHAGGY-like kinase 2/BRASSINAZOLE-RESISTANT 1 module controls lateral root formation in rice.Plant physiology · 2022Article
- Proteomic analysis response of rice (Frontiers in plant science · 2022Article
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Authors and funding
12 authors at 8 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In plants, auxin signalling is initiated by the auxin-promoted interaction between the auxin receptor TIR1, an E3 ubiquitin ligase, and the Aux/IAA transcriptional repressors, which are subsequently degraded by the proteasome. Gain-of-function mutations in the highly conserved domain II of Aux/IAAs abolish the TIR1-Aux/IAA interaction and thus cause an auxin-resistant phenotype. Here we show that peptidyl-prolyl isomerization of rice OsIAA11 catalysed by LATERAL ROOTLESS2 (LRT2), a cyclophilin-type peptidyl-prolyl cis/trans isomerase, directly regulates the stability of OsIAA11. NMR spectroscopy reveals that LRT2 efficiently catalyses the cis/trans isomerization of OsIAA11. The lrt2 mutation reduces OsTIR1-OsIAA11 interaction and consequently causes the accumulation of a higher level of OsIAA11 protein. Moreover, knockdown of the OsIAA11 expression partially rescues the lrt2 mutant phenotype in lateral root development. Together, these results illustrate cyclophilin-catalysed peptidyl-prolyl isomerization promotes Aux/IAA degradation, as a mechanism regulating auxin signalling.
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