ReviewInternational journal of molecular sciences2015
Is Correction of Iron Deficiency a New Addition to the Treatment of the Heart Failure?
Review in International journal of molecular sciences, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 41 citations in OpenAlex.
- Effects of 6-months of oral ferrous and ferric supplement therapy in patients who were hospitalized for decompensated chronic heart failure.The Journal of international medical research · 2019Trial
- Prevalence of anemia in adult heart failure patients at Saint Paul's hospital millennium medical college and Saint Peter's speialized hospital in Addis Ababa Ethiopia: a cross sectional study.BMC cardiovascular disorders · 2026Article
- Iron Deficiency and its Relationship with Chronic Heart Failure- A Review.Cardiovascular & hematological agents in medicinal chemistry · 2025Review
- Role of Iron Deficiency in Heart Failure-Clinical and Treatment Approach: An Overview.Diagnostics (Basel, Switzerland) · 2023Review
- Anaemia among Patients of Heart Failure in a Tertiary Care Centre of Nepal: A Descriptive Cross-sectional Study.JNMA; journal of the Nepal Medical Association · 2021Article
- Effect of ferric-carboxy maltose on oxygen kinetics and functional status in heart failure patients with iron deficiency.Future science OA · 2020Article
- The Influence of Cardiovascular Medications on Iron Metabolism in Patients with Heart Failure.Medicina (Kaunas, Lithuania) · 2019Article
- Anemia profile in patients with congestive heart failure a hospital based observational study.Indian heart journal · 2018Observational
- Anemia in heart failure - from guidelines to controversies and challenges.Anatolian journal of cardiology · 2018Review
- Assessing posterior ocular structures in β-thalassemia minor.International ophthalmology · 2018Article
- Towards Holistic Heart Failure Management-How to Tackle the Iron Deficiency Epidemic?Current heart failure reports · 2017Review
- Cardiac Cachexia: Perspectives for Prevention and Treatment.Arquivos brasileiros de cardiologia · 2017Review
- Anaemia and iron deficiency in heart failure: epidemiological gaps, diagnostic challenges and therapeutic barriers in sub-Saharan Africa.Cardiovascular journal of AfricaReview
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Anemia is present in about 40% of heart failure (HF) patients. Iron deficiency (ID) is present in about 60% of the patients with anemia (about 24% of all HF patients) and in about 40% of patients without anemia (about 24% of all HF patients). Thus ID is present in about half the patients with HF. The ID in HF is associated with reduced iron stores in the bone marrow and the heart. ID is an independent risk factor for severity and worsening of the HF. Correction of ID with intravenous (IV) iron usually corrects both the anemia and the ID. Currently used IV iron preparations are very safe and effective in treating the ID in HF whereas little information is available on the effectiveness of oral iron. In HF IV iron correction of ID is associated with improvement in functional status, exercise capacity, quality of life and, in some studies, improvement in rate of hospitalization for HF, cardiac structure and function, and renal function. Large long-term adequately-controlled intervention studies are needed to clarify the effect of IV iron in HF. Several heart associations suggest that ID should be routinely sought for in all HF patients and corrected if present. In this paper we present our approach to diagnosis and treatment of iron deficiency in heart failure.
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