Evidence map›Paper›PMID 26095435›Full record

Trial reportJournal of the Academy of Nutrition and Dietetics2015

Early weight-loss success identifies nonresponders after a lifestyle intervention in a worksite diabetes prevention trial.

Carla K Miller, Haikady N Nagaraja, Kellie R Weinhold

Open access · bronzeAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of the Academy of Nutrition and Dietetics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 1 pooled it
2.7field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 1 synthesis or guideline pooled it, 41 citations in OpenAlex.

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  5. Sex Moderates Treatment Effects of Integrated Collaborative Care for Comorbid Obesity and Depression: The RAINBOW RCT.Annals of behavioral medicine : a publication of the Society of Behavioral Medicine · 2021
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  7. Early Weight Loss in Behavioral Treatment Predicts Later Rate of Weight Loss and Response to Pharmacotherapy.Annals of behavioral medicine : a publication of the Society of Behavioral Medicine · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Carla K Miller
Haikady N Nagaraja
Kellie R Weinhold
The Ohio State University · US

Funding

Evaluation of a Lifestyle Intervention for Employees with PrediabetesR34DK093907 · NIDDK · OHIO STATE UNIVERSITY · PI MILLER, CARLA K · 2012 to 2013
$464k
NIDDK NIH HHS R34 DK093907NIDDK NIH HHS R34DK093907
6 · The paper itself

Abstract

backgroundPeople with prediabetes are at increased risk for developing type 2 diabetes mellitus. Weight reduction through lifestyle modification can significantly reduce diabetes risk. Yet, weight loss varies among individuals and some people do not achieve clinically meaningful weight loss after treatment.

objectiveOur aim was to evaluate the time point and threshold for achieving ≥5% weight loss after completion of a 16-week worksite, lifestyle intervention for diabetes prevention.

designWeight change before and after the behavioral intervention among participants randomized to the experimental group was examined. PARTICIPANTS/

settingIndividuals with prediabetes aged 18 to 65 years with a body mass index (calculated as kg/m(2)) of 25 to 50 at Ohio State University were eligible.

interventionThe 16-week, group-based intervention, adapted from the Diabetes Prevention Program, was delivered to 32 participants in the experimental group.

main outcome measuresPercent weight loss was assessed weekly during the intervention and at 4- and 7-month follow-up. STATISTICAL ANALYSES PERFORMED: Linear regression modeled the relationship between percent weight loss during month 1 of the intervention and percent weight loss at 4 and 7 months. Logistic regression modeled failure to lose ≥5% weight loss at 4 and 7 months using weekly weight change during the first month of intervention.

resultsPercent weight loss at intervention week 5 was significantly associated with percent weight loss at 4 and 7 months (all P<0.001). Only 11.1% and 12.5% of participants who failed to achieve a 2.5% weight-loss threshold during month 1 achieved ≥5% weight loss at months 4 and 7, respectively.

conclusionsThe first month of lifestyle treatment is a critical period for helping participants achieve weight loss. Otherwise, individuals who fail to achieve at least 2.5% weight loss may benefit from more intensive rescue efforts or stepped-care interventions.

Indexed as

Behavior TherapyLife StylePsychotherapy, GroupAdolescentAdultAgedBody Mass IndexCombined Modality TherapyDiabetes Mellitus, Type 2Diet, ReducingFemaleFollow-Up StudiesHumansMaleMiddle AgedMotor ActivityDiabetes preventionPredictive valueSensitivitySpecificityWeight-loss success

Identifiers

PMID26095435
PMCPMC4554978
OpenAlexW1565208568

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.