Evidence map›Paper›PMID 26094936›Full record

ReviewEpidemiology and infection2016

The diagnosis and treatment of Helicobacter pylori infection in Arctic regions with a high prevalence of infection: Expert Commentary.

B J McMahon, M G Bruce, A Koch, K J Goodman, V Tsukanov, G Mulvad, M L Borresen, F Sacco, D Barrett, S Westby and 1 more

Open access · hybridAbstract readReview
In one paragraph

Review in Epidemiology and infection, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it, 55 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Rate ofFuture science OA · 2025
    Article
  4. Increasing our knowledge about the epidemiology ofInternational journal of circumpolar health · 2024
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Diseases (Basel, Switzerland) · 2022
    Article
  11. Seroprevalence ofAccess microbiology · 2022
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Presence ofJournal of medical microbiology · 2020
    Article
  19. Article
  20. Disparities in Cancer Incidence and Trends among American Indians and Alaska Natives in the United States, 2010-2015.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 7 institutions in 5 countries.

B J McMahonDepartments of Internal Medicine and Surgery,Alaska Native Tribal Health Consortium,Anchorage,AK,USA.
M G BruceArctic Investigations Program,Division of Preparedness and Emerging Infections,National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention,Anchorage,AK,USA.
A KochDepartment of Epidemiology Research,Statens Serum Institute,Copenhagen,Denmark.
K J GoodmanCanadian North Helicobacter pylori Working Group,University of Alberta,Edmonton,Alberta,Canada.
V TsukanovDepartment of State Medical Research Institute for Northern Problems,Siberian Division of Russian Academy of Medical Sciences,Krasnoyarsk,Russia.
G MulvadPrimary Health Care Clinic,Nuuk,Greenland.
M L BorresenDepartment of Epidemiology Research,Statens Serum Institute,Copenhagen,Denmark.
F SaccoDepartments of Internal Medicine and Surgery,Alaska Native Tribal Health Consortium,Anchorage,AK,USA.
D BarrettDepartments of Internal Medicine and Surgery,Alaska Native Tribal Health Consortium,Anchorage,AK,USA.
S WestbyDepartments of Internal Medicine and Surgery,Alaska Native Tribal Health Consortium,Anchorage,AK,USA.
A J ParkinsonArctic Investigations Program,Division of Preparedness and Emerging Infections,National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention,Anchorage,AK,USA.
Alaska Native Tribal Health Consortium · USStatens Serum Institut · DKCenters for Disease Control and Prevention · USIlisimatusarfik · GLNational Center for Emerging and Zoonotic Infectious Diseases · USResearch Institute of Medical Problems of the North · RUUniversity of Alberta · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Helicobacter pylori infection is a major cause of peptic ulcer and is also associated with chronic gastritis, mucosa-associated lymphoid tissue (MALT) lymphoma, and adenocarcinoma of the stomach. Guidelines have been developed in the United States and Europe (areas with low prevalence) for the diagnosis and management of this infection, including the recommendation to 'test and treat' those with dyspepsia. A group of international experts performed a targeted literature review and formulated an expert opinion for evidenced-based benefits and harms for screening and treatment of H. pylori in high-prevalence countries. They concluded that in Arctic countries where H. pylori prevalence exceeds 60%, treatment of persons with H. pylori infection should be limited only to instances where there is strong evidence of direct benefit in reduction of morbidity and mortality, associated peptic ulcer disease and MALT lymphoma and that the test-and-treat strategy may not be beneficial for those with dyspepsia.

Indexed as

Arctic RegionsDyspepsiaGuidelines as TopicHelicobacter InfectionsHelicobacter pyloriHumansLymphoma, B-Cell, Marginal ZonePeptic UlcerPrevalenceAntibiotic resistancegastrointestinal infectionshealth policyHelicobacter pylori

Identifiers

PMID26094936
PMCPMC4697284
OpenAlexW2118680314

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.