Evidence map›Paper›PMID 26094844›Full record

ArticleDrug and alcohol review2016

Pharmacotherapy for alcohol addiction in a patient with alcoholic cirrhosis and massive upper gastrointestinal bleed: A case study.

Samantha Young, Evan Wood, Keith Ahamad

Abstract readCase Reports
In one paragraph

Article in Drug and alcohol review, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Samantha YoungDepartment of Medicine, University of British Columbia, Vancouver, Canada.
Evan WoodDepartment of Medicine, University of British Columbia, Vancouver, Canada.
Keith AhamadUrban Health Research Initiative, St. Paul's Hospital, Vancouver, Canada.
St. Paul's Hospital · CAUniversity of British Columbia · CA

Funding

Mentoring the next generation of addiction clinician scientists while responding to the opioid epidemicR25DA037756 · NIDA · UNIVERSITY OF BRITISH COLUMBIA · PI FAIRBAIRN, NADIA · 2014 to 2023
$3.6M
NIDA NIH HHS R25 DA037756NIDA NIH HHS R25DA037756
6 · The paper itself

Abstract

Alcohol use causes a substantial burden of morbidity and mortality worldwide. The pharmacologic treatment of alcohol dependence has been increasingly studied and proven to improve outcomes in individuals with alcohol use disorder. However, the treatment of alcohol use disorder is often challenging in the context of patients with hepatic impairment as many medications to treat alcohol use disorder are hepatically metabolised or may cause liver toxicity in some instances. We present a case history of an individual with significant medical complications from alcohol use disorder and explore the dilemma faced in prescribing pharmacologic treatment of alcohol use disorder in patients with significant liver dysfunction.

Indexed as

AlcoholismFemaleGastrointestinal HemorrhageHumansLiver Cirrhosis, AlcoholicMiddle Agedaddiction treatmentalcoholismalcohol-related disorderdrug therapyliver cirrhosis

Identifiers

PMID26094844
PMCPMC5266525
OpenAlexW2167828061

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.