ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2016
Sexual activity and function after surgical treatment in patients with (pre)invasive vulvar lesions.
Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed, 25 citations in OpenAlex.
- Symptom Experience After Surgical Treatment for Vulvar Cancer-A Scoping Review.Scandinavian journal of caring sciences · 2025Article
- The vulvar microbiome in lichen sclerosus and high-grade intraepithelial lesions.Frontiers in microbiology · 2023Article
- The Impact of Vulvar Cancer on Psychosocial and Sexual Functioning: A Literature Review.Cancers · 2021Review
- The Human Vulvar Microbiome: A Systematic Review.Microorganisms · 2021Review
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Authors and funding
10 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeSexual activity (SA) and sexual function (SF) are central outcome measures in women affected by preinvasive (vulvar intraepithelial neoplasia, VIN) and invasive (vulvar cancer, VC) vulvar lesions. Data on sexuality after treatment are scarce.
methodsValidated questionnaires including the female sexual function index (FSFI-d) were provided to 166 women with a history of VIN and VC who attended the colposcopy units of the University Medical Center Hamburg-Eppendorf and Asklepios Medical Clinic Altona for follow-up between March 2011 and June 2012. Additional patients (n = 14) assessed the questionnaires online through the website of the German Vulvar Cancer Support Group (VulvaKarzinom SHG e.V.) during the same time period.
resultsTwenty-four patients with VIN and 34 with VC were evaluable. Median age was 51.5 years, with 34 (58.6%) of the patients being postmenopausal. Median time since completion of treatment was 17 months. All women had undergone vulvar surgery (laser/cold knife/combination). Overall, 14 (24.1%) women reported no SA during the last 4 weeks. SF was clearly impaired compared with previously described normal cohorts. SA and SF of active patients did not differ significantly between those with VIN and VC. Analyses contrasting surgical treatment methods yielded no significant associations; likewise, time since diagnosis did not affect SA and SF significantly. Increasing age was negatively associated with most dimensions of the FSFI-d [desire (p = 0.011), arousal (p = 0.004), lubrication (p = 0.003), orgasm (p = 0.013), satisfaction (p = 0.345), pain (p < 0.001)].
conclusionWomen with VIN and VC after surgical treatment are at high risk to suffer from persistent sexual dysfunction especially at higher age.
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