Evidence map›Paper›PMID 26094185›Full record

SynthesisDrug and alcohol dependence2015

Smoking cessation interventions for adults aged 50 or older: A systematic review and meta-analysis.

Danhong Chen, Li-Tzy Wu

Open access · greenAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Drug and alcohol dependence, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed, 6 pooled it
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 6 syntheses or guidelines pooled it, 114 citations in OpenAlex.

  1. Pooled it
  2. What Are the Effective Components of Group-Based Treatment Programs For Smoking Cessation? A Systematic Review and Meta-Analysis.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2023
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  8. The Impact of Older Age on Smoking Cessation Outcomes After Standard Advice to Quit.Journal of applied gerontology : the official journal of the Southern Gerontological Society · 2023
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  20. Implementing Smoking Cessation Telehealth Technologies Within the VHA: Lessons Learned.Federal practitioner : for the health care professionals of the VA, DoD, and PHS · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Danhong ChenDepartment of Psychiatry and Behavioral Sciences, School of Medicine, Duke University Medical Center, BOX 3903, Durham, NC, 27710, USA. Electronic address: danhong_chen@hotmail.com.
Li-Tzy WuDepartment of Psychiatry and Behavioral Sciences, School of Medicine, Duke University Medical Center, BOX 3903, Durham, NC, 27710, USA; Center for Child and Family Policy, Duke University, Durham, NC, USA. Electronic address: litzy.wu@duke.edu.
Duke Medical Center · USDuke University · US

Funding

Substance Abuse & Treatment Gaps in Asians, Pacific Islanders & Multiple-race IndR01MD007658 · NIMHD · DUKE UNIVERSITY · PI WU, LI-TZY · 2013 to 2017
$1.8M
MDMA and Other Hallucinogen Use: Onset and Abuse/DependenceR01DA019623 · NIDA · DUKE UNIVERSITY · PI WU, LI-TZY · 2007 to 2013
$1.1M
Classification of Substance Use Severity and Treatment Outcomes: NIDA CTN StudiesR33DA027503 · NIDA · DUKE UNIVERSITY · PI WU, LI-TZY · 2010 to 2012
$1.1M
Epdemiology of Non-Medical Prescription Anagesic UseR01DA019901 · NIDA · DUKE UNIVERSITY · PI WU, LI-TZY · 2007 to 2009
$416k
NIDA NIH HHS R01 DA019623NIDA NIH HHS R01 DA019901NIDA NIH HHS R33 DA027503NIMHD NIH HHS R01 MD007658
6 · The paper itself

Abstract

backgroundThe older population size has increased substantially, and a considerable proportion of older adults are cigarette smokers. Quitting smoking is associated with reduced health risk. This review is among the first to quantitatively assess the relative efficacy of types of cessation interventions for smokers aged ≥50 years.

methodsWe conducted searches of the Cochrane Library, Embase, MEDLINE, and PsycINFO to identify smoking cessation studies on adults aged ≥50 years. Twenty-nine randomized clinical trials met the inclusion criteria. Three main types of interventions were identified. We analyzed relative cessation rates or Risk Ratios (RRs) between the type of intervention groups and the control group by fixed- and random-effects meta-analyses at the study level. We conducted a weighted least squares meta-regression of cessation rates on trial and sample characteristics to determine sources of outcome heterogeneity.

resultsFixed-effects analysis showed significant treatment effects for pharmacological (RR=3.18, 95% CI: 1.89-5.36), non-pharmacological (RR=1.80, 95% CI: 1.67-1.94), and multimodal interventions (RR=1.61, 95% CI: 1.41-1.84) compared with control group. Estimations based on meta-regression suggested that pharmacological intervention (mean point prevalence abstinence rate (PPA)=26.10%, CI: 15.20-37.00) resembled non-pharmacological (27.97%, CI: 24.00-31.94), and multimodal interventions (36.64%, CI: 31.66-41.62); and non-pharmacological and multimodal interventions had higher PPAs than the control group (18.80%, CI: 14.48-23.12), after adjusting for a number of trial and sample characteristics.

conclusionsA small number of smoking cessation studies examined smokers aged ≥50 years. Additional research is recommended to determine smoking cessation efficacy for diverse older population groups (e.g., ethnic minorities).

Indexed as

Age FactorsCombined Modality TherapyHumansMiddle AgedOdds RatioSmokingSmoking CessationMeta-analysisOlder adultsSmoking cessation interventionsWeighted least squares meta-regression

Identifiers

PMID26094185
PMCPMC4536122
OpenAlexW1556308830

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.