ArticlePlanta2015
Anthocyanin biosynthesis in gerbera cultivar 'Estelle' and its acyanic sport 'Ivory'.
Article in Planta, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 40 citations in OpenAlex.
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- Deep transcriptome and metabolome analysis to dissect untapped spatial dynamics of specialized metabolism in Saussurea costus (Falc.) Lipsch.Functional & integrative genomics · 2025Article
- Function of Anthocyanin and Chlorophyll Metabolic Pathways in the Floral Sepals Color Formation in Different Hydrangea Cultivars.Plants (Basel, Switzerland) · 2025Article
- An LcMYB111-LcHY5 Module Differentially Activates anInternational journal of molecular sciences · 2023Article
- Small RNA and Degradome Sequencing Reveal Roles of miRNAs in the Petal Color Fading ofInternational journal of molecular sciences · 2023Article
- Biostimulants promote the accumulation of carbohydrates and biosynthesis of anthocyanins in 'Yinhongli' plum.Frontiers in plant science · 2022Article
- Functional analysis of the dihydroflavonol 4-reductase family ofHorticulture research · 2022Article
- Polyketide Derivatives in the Resistance ofFrontiers in plant science · 2021Article
- Classification and Association Analysis of Gerbera (Frontiers in plant science · 2021Article
- Cloning and Functional Characterization of Dihydroflavonol 4-Reductase Gene Involved in Anthocyanin Biosynthesis of Chrysanthemum.International journal of molecular sciences · 2020Article
- The R2R3-MYB transcription factor GhMYB1a regulates flavonol and anthocyanin accumulation inHorticulture research · 2020Article
- Hybrid Sequencing of Full-Length cDNA Transcripts of the Medicinal PlantInternational journal of molecular sciences · 2019Article
- mRNA and miRNA Expression Analysis Reveal the Regulation for Flower Spot Patterning inInternational journal of molecular sciences · 2019Article
- Drying the leaves ofFood science & nutrition · 2019Article
- Differential expression of anthocyanin structural genes and transcription factors determines coloration patterns in gerbera flowers.3 Biotech · 2018Article
- Transcriptional control of anthocyanin biosynthesis genes and transcription factors associated with flower coloration patterns in3 Biotech · 2018Article
- Article
- Within leaf variation is the largest source of variation in agroinfiltration of Nicotiana benthamiana.Plant methods · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
MAIN
conclusionIdentification of distinct allelic versions for dihydroflavonol 4-reductase in gerbera cultivars reveals that gerbera DFR enzymes have strong substrate preference in vivo that is not reflected to the activity in vitro. Flavonoids in the model ornamental plant Gerbera hybrida consist of flavones, flavonols and anthocyanins. Anthocyanins accumulate in the adaxial epidermis of petals and give the different cultivars their characteristic red and violet colour. Both pelargonidin and cyanidin derivatives are found in gerbera, but none of the cultivars contain delphinidin. 'Ivory', a cultivar with white petals, is a sport of the pelargonidin-containing pink cultivar 'Estelle', i.e. it originates from an acyanic branch of 'Estelle'. In this work, four different alleles encoding dihydroflavonol 4-reductase (DFR) were identified in gerbera cultivars. We found that, in contrast to 'Estelle' with the functional allele GDFR1-2, 'Ivory' carries a mutation in this gene that results in an inactive enzyme. Interestingly, 'Ivory' also expresses a second, nonmutated allele (GDFR1-3) in petal epidermi, leading to extractable DFR activity but not to anthocyanin biosynthesis. The second allele encodes a protein identical in amino acid sequence to the DFR of the cyanidin-containing variety 'President'. Pelargonidin-containing cultivars do not react to the flavonoid 3'-hydroxylase inhibitor tetcyclacis, but cyanidin-containing cultivars lose their colour, instead of starting to synthesise pelargonidins, indicating the specificity of GDFR1-3 for the cyanidin pathway. This explains why petals of 'Ivory' are white, even when it has lost only one of the two enzymatically functional DFR forms, and shows that anthocyanin biosynthesis in gerbera is under more complex regulation than earlier thought.
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