Evidence map›Paper›PMID 26093635›Full record

ArticleFluids and barriers of the CNS2015

Relation between tag position and degree of visualized cerebrospinal fluid reflux into the lateral ventricles in time-spatial labeling inversion pulse magnetic resonance imaging at the foramen of Monro.

Erik H Middlebrooks, Jeffrey A Bennett, Alissa Old Crow

Abstract read
In one paragraph

Article in Fluids and barriers of the CNS, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Erik H MiddlebrooksDepartment of Radiology, College of Medicine, University of Florida, 1600 SW Archer Rd., PO Box 100374, Gainesville, FL, 32610, USA. ehmiddlebrooks@gmail.com.
Jeffrey A BennettDepartment of Radiology, College of Medicine, University of Florida, 1600 SW Archer Rd., PO Box 100374, Gainesville, FL, 32610, USA. bennja@radiology.ufl.edu.
Alissa Old CrowDepartment of Radiology, College of Medicine, University of Florida, 1600 SW Archer Rd., PO Box 100374, Gainesville, FL, 32610, USA. alissaol@ufl.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTime-spatial labeling inversion pulse (Time-SLIP) magnetic resonance imaging allows non-invasive visualization of cerebrospinal fluid (CSF) movement. Our study evaluated the sensitivity of the Time-SLIP tag placement on the measurement of CSF reflux from the third ventricle into the lateral ventricles via the foramen of Monro.

findingsMultiple Time-SLIP MRI scans were obtained in three healthy volunteers (23-55 years of age) evaluating the observed CSF pulsation and reflux from the third ventricle into the lateral ventricles while varying the placement of the tag. Linear regression was performed to evaluate the effects of tag position on the amount of visualized reflux and pulsation. Variation in the position of the tag relative to the plane of the free margin of the septum pellucidum produced a significant inverse variation in the observed reflux into the lateral ventricles (R(2) = 0.74). The further the distance of the top (superior edge) of the tag from the plane of the free margin of the septum pellucidum, the less reflux into the lateral ventricles was observed (P = 0.006).

conclusionsThe amount of observed CSF reflux into the lateral ventricles in Time-SLIP MR imaging is dependent on the positioning of the CSF tag with decreasing amount of visualized reflux the further caudal the CSF tag is relative to the free margin of the septum pellucidum.

Indexed as

AdultCerebral VentriclesCerebrospinal FluidHumansLateral VentriclesMagnetic Resonance ImagingMiddle AgedPulsatile FlowThird VentricleYoung Adult

Identifiers

PMID26093635
PMCPMC4475619

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.