Evidence map›Paper›PMID 26093287›Full record

ArticleAmerican journal of ophthalmology2015

Association of ocular conditions with narrow angles in different ethnicities.

Roland Y Lee, Brian H Chon, Shuai-Chun Lin, Mingguang He, Shan C Lin

Open access · greenAbstract readComparative Study
In one paragraph

Article in American journal of ophthalmology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Comparison of corneal tomographic parameters between Hispanic and non-Hispanic patients.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2024
    Article
  5. Article
  6. An overview and update of COExperimental and therapeutic medicine · 2023
    Review
  7. Article
  8. Review
  9. COOphthalmology and therapy · 2022
    Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. COJournal of ophthalmology · 2021
    Article
  15. Article
  16. Article
  17. Observational
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Roland Y LeeDepartment of Ophthalmology, University of California, San Francisco, San Francisco, California; Wake Forest University School of Medicine, Winston-Salem, North Carolina.
Brian H ChonDepartment of Ophthalmology, University of California, San Francisco, San Francisco, California.
Shuai-Chun LinDepartment of Ophthalmology, University of California, San Francisco, San Francisco, California.
Mingguang HeDepartment of Ophthalmology, University of California, San Francisco, San Francisco, California; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China.
Shan C LinDepartment of Ophthalmology, University of California, San Francisco, San Francisco, California. Electronic address: LinS@vision.ucsf.edu.
University of California, San Francisco · USSun Yat-sen University · CN

Funding

Rapid-Prototyping and Design CoreP30EY002162 · NEI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI LAKKARAJU, APARNA · 1985 to 2024
$16.8M
NEI NIH HHS EY002162NEI NIH HHS P30 EY002162
6 · The paper itself

Abstract

purposeTo quantify the predictive strength of anterior chamber area (ACA), anterior chamber volume (ACV), anterior chamber width (ACW), lens vault (LV), iris thickness (IT), and iris area (IArea) for 2 angle width parameters, trabecular-iris space area (TISA750) and angle opening distance (AOD750) at 750 μm from the scleral spur, in different ethnicities.

designProspective, cross-sectional study.

methodsAnterior segment optical coherence tomography images for 166 white, 90 African, 75 Hispanic, and 132 Chinese subjects were analyzed. First, ACA, ACV, ACW, LV, IT, and IArea were compared among ethnic groups. Second, associations of TISA750 and AOD750 with ACA, ACV, ACW, LV, IT, and IArea were investigated within each ethnic group using multivariable linear regression models, standardized regression coefficients (β), and coefficients of determination (R(2)).

resultsSignificant ethnic differences were observed in ACA, ACV, ACW, LV, IT, and IArea (all P < .05). ACA, ACV, and LV were significant predictors of TISA750 and AOD750 in all ethnic groups (all P < .001). ACW and IT were significant predictors of AOD750 in white and African subjects (all P < .05). ACW and IT were significant predictors of TISA750 in white subjects (all P < .05). IArea was a significant predictor of AOD750 in Chinese (P < .05). ACA, ACV, and LV had the highest predictive strength for both TISA750 and AOD750 in all ethnic groups based on β and R(2).

conclusionsDespite ethnic differences in ACA, ACV, ACW, LV, IT, and IArea, the same 3 anterior segment parameters (ACA, ACV, and LV) were the strongest predictors of angle width (TISA750 and AOD750) in all 4 ethnic groups.

Indexed as

EthnicityAgedAnterior ChamberAsian PeopleBiometryBlack or African AmericanChinaCross-Sectional StudiesFemaleGlaucoma, Angle-ClosureHispanic or LatinoHumansIrisLens, CrystallineMaleMiddle Aged

Identifiers

PMID26093287
PMCPMC4543433
OpenAlexW1778613503

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.