Evidence map›Paper›PMID 26092401›Full record

ReviewBrain research2016

Epigenetics in NG2 glia cells.

Sarah Moyon, Jialiang Liang, Patrizia Casaccia

Abstract readReview
In one paragraph

Review in Brain research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. Chd7 Collaborates with Sox2 to Regulate Activation of Oligodendrocyte Precursor Cells after Spinal Cord Injury.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2017
    Article
  11. Article
  12. The regulatory mechanisms of NG2/CSPG4 expression.Cellular & molecular biology letters · 2017
    Review
  13. Review
  14. Review
  15. The Role of NG2 Proteoglycan in Glioma.Translational oncology · 2016
    Review
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Sarah MoyonDepartment of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Jialiang LiangDepartment of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Patrizia CasacciaDepartment of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Corinne Goldsmith Dickinson Center for Multiple Sclerosis, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA. Electronic address: patrizia.casaccia@mssm.edu.

Funding

Role of cell cycle regulators in differentiationR01NS052738 · NINDS · UNIV OF MED/DENT NJ-R W JOHNSON MED SCH · PI CANOLL, PETER, CASACCIA, PATRIZIA · 2007 to 2020
$4.6M
Histone Deacetylation in Oligodendrocyte DifferentiationR37NS042925 · NINDS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI CASACCIA, PATRIZIA · 2012 to 2018
$4.3M
Histone deacetylation in oligodendrocyte differentiationR01NS042925 · NINDS · UNIV OF MED/DENT NJ-R W JOHNSON MED SCH · PI CASACCIA, PATRIZIA · 2003 to 2011
$3.9M
NINDS NIH HHS R01 NS042925NINDS NIH HHS R01 NS052738NINDS NIH HHS R37 NS042925
6 · The paper itself

Abstract

The interplay of transcription and epigenetic marks is essential for oligodendrocyte progenitor cell (OPC) proliferation and differentiation during development. Here, we review the recent advances in this field and highlight mechanisms of transcriptional repression and activation involved in OPC proliferation, differentiation and plasticity. We also describe how dysregulation of these epigenetic events may affect demyelinating disorders, and consider potential ways to manipulate NG2 cell behavior through modulation of the epigenome. This article is part of a Special Issue entitled SI:NG2-glia(Invited only).

Indexed as

AnimalsAntigensCell DifferentiationCell ProliferationChondroitin Sulfate Proteoglycan 4Epigenesis, GeneticHumansNeurogliaProteoglycansAntigensChondroitin Sulfate Proteoglycan 4ProteoglycansDifferentiationEpigeneticsNG2 cellOligodendrocyte progenitor cellProliferation

Identifiers

PMID26092401
PMCPMC4683112

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.