Evidence map›Paper›PMID 26092378›Full record

ReviewJournal of dental research2015

The Role of Autophagy in Salivary Gland Homeostasis and Stress Responses.

M Morgan-Bathke, H H Lin, D K Ann, K H Limesand

Abstract readReview
In one paragraph

Review in Journal of dental research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Current State of Knowledge on Salivary Gland Cancers.Critical reviews in oncogenesis · 2018
    Review
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

M Morgan-BathkeDepartment of Nutritional Sciences, University of Arizona, Tucson, AZ, USA.
H H LinDepartment of Molecular and Cellular Biology, Beckman Research Institute, City of Hope, Duarte, CA, USA.
D K AnnDiabetes and Metabolic Diseases Research, Beckman Research Institute, City of Hope, Duarte, CA, USA.
K H LimesandDepartment of Nutritional Sciences, University of Arizona, Tucson, AZ, USA limesank@u.arizona.edu.
City of Hope · USUniversity of Arizona · US

Funding

MOLECULAR PROGRAMMING OF SALIVARY GLAND GENE EXPRESSIONR01DE010742 · NIDCR · UNIVERSITY OF SOUTHERN CALIFORNIA · PI ANN, DAVID K. · 1993 to 2013
$5.1M
Functional restoration through salivary progenitor label retaining cellsR01DE023534 · NIDCR · UNIVERSITY OF ARIZONA · PI ANN, DAVID K., LIMESAND, KIRSTEN H · 2014 to 2018
$1.9M
Autophagy & Functional Restoration of Irradiated Salivary GlandsRC1DE020335 · NIDCR · UNIVERSITY OF ARIZONA · PI ANN, DAVID K., LIMESAND, KIRSTEN H · 2009 to 2010
$898k
Molecular Characterization of Autophagy in Salivary Gland TumorsR21DE023298 · NIDCR · BECKMAN RESEARCH INSTITUTE/CITY OF HOPE · PI ANN, DAVID K. · 2013 to 2014
$462k
NIDCR NIH HHS R01 DE010742NIDCR NIH HHS R01 DE023534NIDCR NIH HHS R01 R01DE10742NIDCR NIH HHS R21 DE023298NIDCR NIH HHS RC1 DE020335
6 · The paper itself

Abstract

Autophagy is a catabolic process that has been shown to have a role in many cellular processes including the removal of excessive or damaged proteins and protein aggregates. The salivary glands play a critical role in oral health, and their secretory capacity may be critically intertwined with the autophagic process. This review describes the role of autophagy activation in normal salivary gland homeostasis and during the glandular stress responses of therapeutic radiation, ductal ligation, autoimmunity, and salivary gland adenoid cystic carcinoma.

Indexed as

AnimalsAutoimmune DiseasesAutophagyCarcinoma, Adenoid CysticDisease Models, AnimalHomeostasisHumansLigationSalivary Gland NeoplasmsSalivary GlandsSirolimusStress, PhysiologicalSirolimuscancerductal ligationradiationrapaloguessalivary physiologySjogren’s syndrome

Identifiers

PMID26092378
PMCPMC4530390
OpenAlexW1514626972

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.