ReviewCurrent atherosclerosis reports2015
Statins in Intracerebral Hemorrhage.
Review in Current atherosclerosis reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 41 citations in OpenAlex.
- The role of stem cells and their engineering strategies in the repair of nerve damage in intracerebral hemorrhage.Cell & bioscience · 2026Review
- Review
- Early statin use might reduce the hemorrhagic transformation among acute ischemic stroke patients with recanalization therapy: a retrospective cohort study.Frontiers in pharmacology · 2025Article
- Effect of statin therapy patterns on readmission and mortality in patients with intracerebral hemorrhage.Journal of thrombosis and thrombolysis · 2024Article
- Low-density Lipoprotein Cholesterol Reduction Therapies for Secondary Prevention in Patients with Stroke: A Network Meta-analysis.Current neuropharmacology · 2024Article
- Genetically predicted on-statin LDL response is associated with higher intracerebral haemorrhage risk.Brain : a journal of neurology · 2022Article
- Review
- A practical approach to the management of cerebral amyloid angiopathy.International journal of stroke : official journal of the International Stroke Society · 2021Review
- Prediction of amyloid β PET positivity using machine learning in patients with suspected cerebral amyloid angiopathy markers.Scientific reports · 2020Article
- Review
- Treatment Approaches to Lacunar Stroke.Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association · 2019Review
- Statins and Risk of Intracerebral Haemorrhage in a Stroke-Free Population: A Nationwide Danish Propensity Score Matched Cohort Study.EClinicalMedicine · 2019Article
- Updates on Prevention of Hemorrhagic and Lacunar Strokes.Journal of stroke · 2018Article
- Statins do not increase Markers of Cerebral Angiopathies in patients with Cardioembolic Stroke.Scientific reports · 2018Article
- Mixed-location cerebral hemorrhage/microbleeds: Underlying microangiopathy and recurrence risk.Neurology · 2018Article
- The increasing impact of cerebral amyloid angiopathy: essential new insights for clinical practice.Journal of neurology, neurosurgery, and psychiatry · 2017Review
- Stroke Risk Factors, Genetics, and Prevention.Circulation research · 2017Review
- Article
- Diagnosis and Management of Acute Intracerebral Hemorrhage.Emergency medicine clinics of North America · 2016Review
- Cerebral Microhemorrhages: Significance, Associations, Diagnosis, and Treatment.Current treatment options in neurology · 2016Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
While statins play an indisputable role in primary and secondary prevention of ischemic cardiovascular and cerebrovascular disease, a concern exists regarding a possible association between low lipoprotein levels and statin use on the risk of intracerebral hemorrhage (ICH). While these data may incline physicians to discontinue statins after ICH, an increasing amount of preclinical and clinical evidence suggests that statins might have a beneficial effect on outcome and recovery in this context that goes beyond lipid lowering effects. Different etiologies of ICH and the related risk of recurrence should also be taken into account when deciding about statin use/avoidance in patients with high risk of ICH. The problem is compounded by paucity of data from randomized controlled trials and well-designed prospective observational studies. This review will discuss the existing evidence on potential interactions between statins and risk of ICH as well as outcomes in order to provide practical recommendations for clinical decision-making.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.