Evidence map›Paper›PMID 26092037›Full record

ArticleEnvironmental health : a global access science source2015

Parma consensus statement on metabolic disruptors.

Jerrold J Heindel, Frederick S Vom Saal, Bruce Blumberg, Patrizia Bovolin, Gemma Calamandrei, Graziano Ceresini, Barbara A Cohn, Elena Fabbri, Laura Gioiosa, Christopher Kassotis and 21 more

Erratum issuedOpen access · goldAbstract readConsensus Statement
In one paragraph

Article in Environmental health : a global access science source, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 117 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
117citing papers in PubMed, 4 pooled it
13.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

117 citing papers in PubMed, 4 syntheses or guidelines pooled it, 216 citations in OpenAlex.

  1. Pooled it
  2. Relationship between Prenatal or Postnatal Exposure to Pesticides and Obesity: A Systematic Review.International journal of environmental research and public health · 2021
    Pooled it
  3. Pooled it
  4. Association between Exposure toEnvironmental health perspectives · 2017
    Pooled it
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57 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

31 authors at 16 institutions in 4 countries.

Jerrold J HeindelDivision of Extramural Research and Training, National Institute of Environmental Health Sciences, Research Triangle Park, NC, USA. heindelj@niehs.nih.gov.
Frederick S Vom SaalDivision of Biological Sciences, University of Missouri, Columbia, MO, USA.
Bruce BlumbergDepartment of Developmental and Cell Biology, University of California, Irvine, CA, USA.
Patrizia BovolinDepartment of Life Sciences and Systems Biology, University of Turin, Turin, Italy.
Gemma CalamandreiDepartment of Cell Biology and Neurosciences, Insituto Superiore di Sanita, Rome, Italy.
Graziano CeresiniDepartment of Clinical and Experimental Medicine, University of Parma, Parma, Italy.
Barbara A CohnPublic Health Institute, Berkeley, CA, USA.
Elena FabbriInterdepartment Center for Environmental Science Research, University of Bologna, Ravenna, Italy.
Laura GioiosaDepartment of Neuroscience, University of Parma, Parma, Italy.
Christopher KassotisDivision of Biological Sciences, University of Missouri, Columbia, MO, USA.
Juliette LeglerDepartment of Toxicology and Environmental Health, VU University Amsterdam, Amsterdam, Netherlands.
Michele La MerrillDepartment of Environmental Toxicology, University of California, Davis, CA, USA.
Laura RizzirDepartment of Health Sciences, University of Milano-Bicocca, Monza, Italy.
Ronit MachtingerSheba Medical Center and Tel-Aviv University, Tel -Aviv, Israel.
Alberto MantovaniInstituto Superiore di Sanita, Rome, Italy.
Michelle A MendezSchool of Public Health, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Luisa MontaniniDepartment of Pediatrics, University of Parma, Parma, Italy.
Laura MolteniUniversity of Milano-Bicocca, Monza, Italy.
Susan C NagelDepartment of Obstetrics, Gynecology and Women's Health, University of Missouri, Columbia, MO, USA.
Stefano ParmigianiFaculty of Medicine, University of Parma, Parma, Italy.
Giancarlo PanzicaDepartment of Neuroscience and Neuroscience Institute Cavalieri Ottolenghi (NICO), University of Turin, Turin, Italy.
Silvia PaterliniDepartment of Neuroscience and Neuroscience Institute Cavalieri Ottolenghi (NICO), University of Turin, Turin, Italy.
Valentina PomattoDepartment of Life Sciences and Systems Biology, University of Turin, Turin, Italy.
Jérôme RuzzinDepartment of Biology, University of Bergen, Bergen, Norway.
Giorgio SartorDepartment of Pharmacy and Biotechnology, University of Bologna, Bologna, Italy.
Thaddeus T SchugDivision of Extramural Research and Training, National Institute of Environmental Health Sciences, Research Triangle Park, NC, USA.
Maria E StreetDepartment of Pediatrics, University Hospital, Parma, Italy.
Alexander SuvorovDivision of Biological Sciences, University of Missouri, Columbia, MO, USA.
Riccardo VolpiDepartment of Internal Medicine, University of Parma, Parma, Italy.
R Thomas ZoellerDepartment of Biology, University of Massachusetts, Amherst, MA, USA.
Paola PalanzaDepartment of Neuroscience, University of Parma, Parma, Italy.
University of Parma · ITUniversity of Missouri · USUniversity of Turin · ITIstituto Superiore di Sanità · ITNational Institute of Environmental Health Sciences · USUniversity of Bologna · ITUniversity of Milano-Bicocca · ITNeuroscience Institute · ITPublic Health Institute · USSheba Medical Center · ILUniversity of Bergen · NOUniversity of California, Davis · USUniversity of California, Irvine · USUniversity of Massachusetts Amherst · USUniversity of Missouri Health System · USUniversity of North Carolina at Chapel Hill · US

Funding

Transgenerational obesity caused by ancestral exposure to obesogens in utero: changes in germline genomic architecture, roles of gonadal somatic cells, and metabolomic analysis of sexual dimorphismR01ES023316 · NIEHS · UNIVERSITY OF CALIFORNIA-IRVINE · PI BRUCE BLUMBERG, TOSHIHIRO SHIODA · 2013 to 2026
$8.3M
6 · The paper itself

Abstract

A multidisciplinary group of experts gathered in Parma Italy for a workshop hosted by the University of Parma, May 16-18, 2014 to address concerns about the potential relationship between environmental metabolic disrupting chemicals, obesity and related metabolic disorders. The objectives of the workshop were to: 1. Review findings related to the role of environmental chemicals, referred to as "metabolic disruptors", in obesity and metabolic syndrome with special attention to recent discoveries from animal model and epidemiology studies; 2. Identify conclusions that could be drawn with confidence from existing animal and human data; 3. Develop predictions based on current data; and 4. Identify critical knowledge gaps and areas of uncertainty. The consensus statements are intended to aid in expanding understanding of the role of metabolic disruptors in the obesity and metabolic disease epidemics, to move the field forward by assessing the current state of the science and to identify research needs on the role of environmental chemical exposures in these diseases. We propose broadening the definition of obesogens to that of metabolic disruptors, to encompass chemicals that play a role in altered susceptibility to obesity, diabetes and related metabolic disorders including metabolic syndrome.

Indexed as

Consensus Statements as TopicCongresses as TopicDiabetes MellitusEnvironmental ExposureEnvironmental PollutantsHazardous SubstancesHumansItalyMetabolic SyndromeObesityEnvironmental PollutantsHazardous Substances

Identifiers

PMID26092037
PMCPMC4473834
OpenAlexW2151901442

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.