Trial reportSurgical endoscopy2016
Laparoscopic microwave thermosphere ablation of malignant liver tumors: an initial clinical evaluation.
Trial report in Surgical endoscopy, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 24 citations in OpenAlex.
- Pooled it
- Liver microwave ablation: a systematic review of various FDA-approved systems.European radiology · 2019Pooled it
- Is Laparoscopic Microwave Ablation Truly Noninferior to Percutaneous Ablation in Early Stage Hepatocellular Carcinoma? A Critical Reassessment.Annals of surgical oncology · 2025Article
- Optimizing microwave ablation planning with the ablation success ratio.Scientific reports · 2025Article
- Radiofrequency ablation versus microwave ablation for colorectal liver metastases: long-term results of a retrospective cohort surgical experience.Hepatobiliary surgery and nutrition · 2024Article
- Comparative Study of Ablation Zone of EMPRINT HP Microwave Device with Contemporary 2.4 GHz Microwave Devices in an Ex Vivo Porcine Liver Model.Diagnostics (Basel, Switzerland) · 2023Article
- Recent therapeutics in hepatocellular carcinoma.American journal of cancer research · 2023Review
- Comparison of Ablation Volume Between EmprintJournal of hepatocellular carcinoma · 2023Article
- Microwave ablation vs. cryoablation for treatment of primary and metastatic pulmonary malignant tumors.Molecular and clinical oncology · 2022Article
- On Efficacy of Microwave Ablation in the Thermal Treatment of an Early-Stage Hepatocellular Carcinoma.Cancers · 2021Article
- Role of thermal ablation in the management of colorectal liver metastasis.Hepatobiliary surgery and nutrition · 2020Review
- The relationship between applied energy and ablation zone volume in patients with hepatocellular carcinoma and colorectal liver metastasis.European radiology · 2018Article
- A comparison between 915 MHz and 2450 MHz microwave ablation systems for the treatment of small diameter lung metastases.Diagnostic and interventional radiology (Ankara, Turkey)Article
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMicrowave ablation (MWA) has been recently recognized as a technology to overcome the limitations of radiofrequency ablation. The aim of the current study was to evaluate the safety and efficacy of a new 2.45-GHz thermosphere MWA system in the treatment of malignant liver tumors.
methodsThis was a prospective IRB-approved study of 18 patients with malignant liver tumors treated with MWA within a 3-month time period. Tumor sizes and response to MWA were obtained from triphasic liver CT scans done before and after MWA. The ablation zones were assessed for complete tumor response and spherical geometry.
resultsThere were a total of 18 patients with an average of three tumors measuring 1.4 cm (range 0.2-4). Ablations were performed laparoscopically in all, but three patients who underwent combined liver resection. A single ablation was created in 72% and overlapping ablations in 28% of lesions. Total ablation time per patient was 15.6 ± 1.9 min. There was no morbidity or mortality. At 2-week CT scans, there was 100% tumor destruction, with no residual lesions. Roundness indices A, B and transverse were 1.1, 0.9 and 0.9, respectively, confirming the spherical nature of ablation zones.
conclusionsTo the best of our knowledge, this is the first report of a new thermosphere MWA technology in the laparoscopic treatment of malignant liver tumors. The results demonstrate the safety of the technology, with satisfactory spherical ablation zones seen on post-procedural CT scans.
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