ArticleBrain imaging and behavior2016
Preliminary evidence of reduced brain network activation in patients with post-traumatic migraine following concussion.
Article in Brain imaging and behavior, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.
- Subtypes of Sport-Related Concussion: a Systematic Review and Meta-cluster Analysis.Sports medicine (Auckland, N.Z.) · 2020Pooled it
- Preliminary Evaluation of the Circle Sequencing Task (CST) as a Cognitive-Motor Tool for Concussion Assessment.Sports (Basel, Switzerland) · 2026Article
- Towards defining biomarkers to evaluate concussions using virtual reality and a moving platform (BioVRSea).Scientific reports · 2022Article
- Brain Network Analysis of EEG Recordings Can Be Used to Assess Cognitive Function in Teenagers With 15q13.3 Microdeletion Syndrome.Frontiers in neuroscience · 2021Article
- Increased Risk of Musculoskeletal Injury Following Sport-Related Concussion: A Perception-Action Coupling Approach.Sports medicine (Auckland, N.Z.) · 2020Article
- Unifying Pathophysiological Explanations for Sports-Related Concussion and Concussion Protocol Management: Literature Review.Journal of experimental neuroscience · 2019Review
- No Seasonal Changes in Cognitive Functioning Among High School Football Athletes: Implementation of a Novel Electrophysiological Measure and Standard Clinical Measures.Clinical journal of sport medicine : official journal of the Canadian Academy of Sport Medicine · 2018Observational
- Differences in Callosal and Forniceal Diffusion between Patients with and without Postconcussive Migraine.AJNR. American journal of neuroradiology · 2017Article
- Preliminary investigation of Brain Network Activation (BNA) and its clinical utility in sport-related concussion.Brain injury · 2017Article
- Brain Network Activation Technology Does Not Assist with Concussion Diagnosis and Return to Play in Football Athletes.Frontiers in neurology · 2017Article
- Post-Concussive Syndrome: a Focus on Post-Traumatic Headache and Related Cognitive, Psychiatric, and Sleep Issues.Current neurology and neuroscience reports · 2016Review
- Investigating a Novel Measure of Brain Networking Following Sports Concussion.International journal of sports medicine · 2016Article
- Brain Network Activation Analysis Utilizing Spatiotemporal Features for Event Related Potentials Classification.Frontiers in computational neuroscience · 2016Article
- The Effects of External Jugular Compression Applied during Head Impact Exposure on Longitudinal Changes in Brain Neuroanatomical and Neurophysiological Biomarkers: A Preliminary Investigation.Frontiers in neurology · 2016Article
- Stability of an ERP-based measure of brain network activation (BNA) in athletes: A new electrophysiological assessment tool for concussion.Brain injury · 2016Article
- Family History of Migraine Associated With Posttraumatic Migraine Symptoms Following Sport-Related Concussion.The Journal of head trauma rehabilitationObservational
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
Abstract
Post-traumatic migraine (PTM) (i.e., headache, nausea, light and/or noise sensitivity) is an emerging risk factor for prolonged recovery following concussion. Concussions and migraine share similar pathophysiology characterized by specific ionic imbalances in the brain. Given these similarities, patients with PTM following concussion may exhibit distinct electrophysiological patterns, although researchers have yet to examine the electrophysiological brain activation in patients with PTM following concussion. A novel approach that may help differentiate brain activation in patients with and without PTM is brain network activation (BNA) analysis. BNA involves an algorithmic analysis applied to multichannel EEG-ERP data that provides a network map of cortical activity and quantitative data during specific tasks. A prospective, repeated measures design was used to evaluate BNA (during Go/NoGo task), EEG-ERP, cognitive performance, and concussion related symptoms at 1, 2, 3, and 4 weeks post-injury intervals among athletes with a medically diagnosed concussion with PTM (n = 15) and without (NO-PTM) (n = 22); and age, sex, and concussion history matched controls without concussion (CONTROL) (n = 20). Participants with PTM had significantly reduced BNA compared to NO-PTM and CONTROLS for Go and NoGo components at 3 weeks and for NoGo component at 4 weeks post-injury. The PTM group also demonstrated a more prominent deviation of network activity compared to the other two groups over a longer period of time. The composite BNA algorithm may be a more sensitive measure of electrophysiological change in the brain that can augment established cognitive assessment tools for detecting impairment in individuals with PTM.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.