Evidence map›Paper›PMID 26091704›Full record

ArticleEuropean journal of nuclear medicine and molecular imaging2015

MR-based attenuation correction for cardiac FDG PET on a hybrid PET/MRI scanner: comparison with standard CT attenuation correction.

Jan Vontobel, Riccardo Liga, Mathias Possner, Olivier F Clerc, Fran Mikulicic, Patrick Veit-Haibach, Edwin E G W Ter Voert, Tobias A Fuchs, Julia Stehli, Aju P Pazhenkottil and 6 more

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In one paragraph

Article in European journal of nuclear medicine and molecular imaging, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

  1. Trial
  2. Reduction of [EJNMMI physics · 2024
    Article
  3. Article
  4. Assessing the qualitative and quantitative impacts of simple two-class vs multiple tissue-class MR-based attenuation correction for cardiac PET/MR.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021
    Article
  5. Article
  6. Myocardial perfusion imaging in cardiac sarcoidosis: A "sine qua non" for prognosis assessment?Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021
    Article
  7. Evaluation of quantitative CMR perfusion imaging by comparison with simultaneousJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021
    Article
  8. Myocardial creep-induced misalignment artifacts in PET/MR myocardial perfusion imaging.European journal of nuclear medicine and molecular imaging · 2021
    Article
  9. Attenuation correction for human PET/MRI studies.Physics in medicine and biology · 2020
    Article
  10. Hybrid PET/MR imaging in myocardial inflammation post-myocardial infarction.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2020
    Review
  11. Review
  12. PET-derived bone information from 18F-sodium fluoride: A perfect match for whole-body PET/MR attenuation correction?Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2020
    Article
  13. Article
  14. Assessment of attenuation correction for myocardial PET imaging using combined PET/MRI.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2019
    Article
  15. Review
  16. Review
  17. Article
  18. Article
  19. The foundation layer of quantitative cardiac PET/MRI: Attenuation correction. Again.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2017
    Article
  20. Cardiovascular PET/MR imaging: Quo Vadis?Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2017
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Jan VontobelDepartment of Nuclear Medicine, University Hospital Zurich, Ramistrasse 100, 8091, Zurich, Switzerland.
Riccardo Liga
Mathias Possner
Olivier F Clerc
Fran Mikulicic
Patrick Veit-Haibach
Edwin E G W Ter Voert
Tobias A Fuchs
Julia Stehli
Aju P Pazhenkottil
Dominik C Benz
Christoph Gräni
Oliver Gaemperli
Bernhard Herzog
Ronny R Buechel
Philipp A Kaufmann

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe aim of this study was to evaluate the feasibility of attenuation correction (AC) for cardiac (18)F-labelled fluorodeoxyglucose (FDG) positron emission tomography (PET) using MR-based attenuation maps.

methodsWe included 23 patients with no known cardiac history undergoing whole-body FDG PET/CT imaging for oncological indications on a PET/CT scanner using time-of-flight (TOF) and subsequent whole-body PET/MR imaging on an investigational hybrid PET/MRI scanner. Data sets from PET/MRI (with and without TOF) were reconstructed using MR AC and semi-quantitative segmental (20-segment model) myocardial tracer uptake (per cent of maximum) and compared to PET/CT which was reconstructed using CT AC and served as standard of reference.

resultsExcellent correlations were found for regional uptake values between PET/CT and PET/MRI with TOF (n = 460 segments in 23 patients; r = 0.913; p < 0.0001) with narrow Bland-Altman limits of agreement (-8.5 to +12.6 %). Correlation coefficients were slightly lower between PET/CT and PET/MRI without TOF (n = 460 segments in 23 patients; r = 0.851; p < 0.0001) with broader Bland-Altman limits of agreement (-12.5 to +15.0 %). PET/MRI with and without TOF showed minimal underestimation of tracer uptake (-2.08 and -1.29 %, respectively), compared to PET/CT.

conclusionRelative myocardial FDG uptake obtained from MR-based attenuation corrected FDG PET is highly comparable to standard CT-based attenuation corrected FDG PET, suggesting interchangeability of both AC techniques.

Indexed as

ArtifactsAdultAgedAlgorithmsCardiac Imaging TechniquesFeasibility StudiesFemaleFluorodeoxyglucose F18HumansImage EnhancementMagnetic Resonance ImagingMaleMiddle AgedMultimodal ImagingMyocardiumPositron-Emission TomographyFluorodeoxyglucose F18Radiopharmaceuticals

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.