SynthesisPloS one2015
The Value of BISAP Score for Predicting Mortality and Severity in Acute Pancreatitis: A Systematic Review and Meta-Analysis.
Synthesis in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 74 papers, 5 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
74 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- AEG-AESPANC-OPGE-SIED-SPG Ibero-Latin American Guidelines on Acute Pancreatitis (iLATAM-AP).United European gastroenterology journal · 2026Guideline
- Pooled it
- Clinical usefulness of scoring systems to predict severe acute pancreatitis: A systematic review and meta-analysis with pre and post-test probability assessment.United European gastroenterology journal · 2023Pooled it
- Diagnostic Value of Neutrophil-Lymphocyte Ratio for Predicting the Severity of Acute Pancreatitis: A Meta-Analysis.Disease markers · 2020Pooled it
- Pharmacological interventions for acute pancreatitis.The Cochrane database of systematic reviews · 2017Pooled it
- Usefulness of Random Forest Algorithm in Predicting Severe Acute Pancreatitis.Frontiers in cellular and infection microbiology · 2022Trial
- Gallstone Pancreatitis: Admission Versus Normal Cholecystectomy-a Randomized Trial (Gallstone PANC Trial).Annals of surgery · 2019Trial
- Diagnostic Performance of the Uric Acid-To-Albumin Ratio in Predicting Severity of Acute Pancreatitis.JGH open : an open access journal of gastroenterology and hepatology · 2026Article
- Article
- Incremental Prognostic Value of the Admission Systemic Immune-Inflammation Index Beyond BISAP for Early Risk Stratification of Acute Pancreatitis in the Emergency Department.Journal of clinical medicine · 2026Article
- Which fluid resuscitation strategy is associated with shorter length of stay in mild acute pancreatitis? Interaction between crystalloid type and administration rate.BMC gastroenterology · 2026Article
- Are BISAP and APACHE II scores still useful to identify high-risk patients in acute pancreatitis? A retrospective multicenter analysis on 450 patients.Updates in surgery · 2026Article
- Management and Prediction of Acute Pancreatitis Severity Using AI: A Surgical Perspective.Diagnostics (Basel, Switzerland) · 2026Review
- Predicting infected pancreatic necrosis in acute pancreatitis using machine learning models and feature selection.Scientific reports · 2026Article
- Spexin as a Novel Biomarker for Predicting Disease Severity and Mortality in Acute Pancreatitis.International journal of molecular sciences · 2026Article
- Article
- C - reactive protein to albumin ratio as predictor of severity and outcome in acute pancreatitis.Bioinformation · 2026Article
- Application of D-LA and APOB/A1 combined with SIRI score in acute pancreatitis and concurrent infectious pancreatic necrosis.American journal of translational research · 2026Article
- Factors Associated with ICU Admission and In-Hospital Mortality in Patients with Acute Pancreatitis: A Single-Center Retrospective Study.Journal of inflammation research · 2026Article
- Article
14 more citing papers are in PubMed but not listed here.
Corrections and comments
- Erratum issued
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe Bedside Index for Severity in Acute Pancreatitis (BISAP) score has been developed to identify patients at high risk for mortality or severe disease early during the course of acute pancreatitis. We aimed to undertake a meta-analysis to quantify the accuracy of BISAP score for predicting mortality and severe acute pancreatitis (SAP). MATERIALS AND
methodsWe searched the databases of Pubmed, Embase, and the Cochrane Library to identify studies using the BISAP score to predict mortality or SAP. The pooled sensitivity, specificity, likelihood ratios, and diagnostic odds ratio (DOR) were calculated from each study and were compared with the traditional scoring systems.
resultsTwelve cohorts from 10 studies were included. The overall sensitivity of a BISAP score of ≥3 for mortality was 56% (95% CI, 53%-60%), with a specificity of 91% (95% CI, 90%-91%). The positive and negative likelihood ratios were 5.65 (95% CI, 4.23-7.55) and 0.48 (95% CI, 0.41-0.56), respectively. Regarding the outcome of SAP, the pooled sensitivity was 51% (43%-60%), and the specificity was 91% (89%-92%). The pooled positive and negative likelihood ratios were 7.23 (4.21-12.42) and 0.56 (0.44-0.71), respectively. Compared with BISAP score, the Ranson criteria and APACHEⅡscore showed higher sensitivity and lower specificity for both outcomes.
conclusionsThe BISAP score was a reliable tool to identify AP patients at high risk for unfavorable outcomes. Compared with the Ranson criteria and APACHEⅡscore, BISAP score outperformed in specificity, but having a suboptimal sensitivity for mortality as well as SAP.
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