ArticlePLoS neglected tropical diseases2015
Buruli Ulcer Disease and Its Association with Land Cover in Southwestern Ghana.
Article in PLoS neglected tropical diseases, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 43 citations in OpenAlex.
- Human-induced pressures and environmental factors drive the distribution of neglected tropical disease Buruli ulcer.Communications medicine · 2026Article
- Nonlinear and potential driving impacts of meteorological and air pollution factors on influenza-like illness in Jinan, China.BMC public health · 2025Article
- Systematic review: Global host range, case fatality and detection rates ofJournal of clinical tuberculosis and other mycobacterial diseases · 2024Review
- ProfilingFuture science OA · 2023Review
- Perceived water-related risk factors of Buruli ulcer in two villages of south-central Côte d'Ivoire.PLoS neglected tropical diseases · 2022Article
- Utilising community volunteers can increase the detection and referral of Buruli ulcer cases in endemic communities in Southeast, Nigeria.Tropical diseases, travel medicine and vaccines · 2022Article
- Developing spatio-temporal approach to predict economic dynamics based on online news.Scientific reports · 2022Article
- Understanding the transmission of Mycobacterium ulcerans: A step towards controlling Buruli ulcer.PLoS neglected tropical diseases · 2021Review
- Mapping suitability for Buruli ulcer at fine spatial scales across Africa: A modelling study.PLoS neglected tropical diseases · 2021Article
- Stable and Local Reservoirs of Mycobacterium ulcerans Inferred from the Nonrandom Distribution of Bacterial Genotypes, Benin.Emerging infectious diseases · 2020Article
- The complex associations of climate variability with seasonal influenza A and B virus transmission in subtropical Shanghai, China.The Science of the total environment · 2020Article
- Association of sociodemographic factors and internet query data with pertussis infections in Shandong, China.Epidemiology and infection · 2019Article
- Resurgence of Pertussis Infections in Shandong, China: Space-Time Cluster and Trend Analysis.The American journal of tropical medicine and hygiene · 2019Article
- Modelling the spatial distribution of aquatic insects (Order Hemiptera) potentially involved in the transmission of Mycobacterium ulcerans in Africa.Parasites & vectors · 2018Article
- Exploring links between greenspace and sudden unexpected death: A spatial analysis.Environment international · 2018Article
- Inverse relationship between urban green space and childhood autism in California elementary school districts.Environment international · 2017Article
- Seasonal Pattern of Mycobacterium ulcerans, the Causative Agent of Buruli Ulcer, in the Environment in Ghana.Microbial ecology · 2017Article
- Landscape Fragmentation as a Risk Factor for Buruli Ulcer Disease in Ghana.The American journal of tropical medicine and hygiene · 2016Article
- Burden and Historical Trend of Buruli Ulcer Prevalence in Selected Communities along the Offin River of Ghana.PLoS neglected tropical diseases · 2016Article
- Influence of Climate Extremes and Land Use on Fecal Contamination of Shallow Tubewells in Bangladesh.Environmental science & technology · 2016Article
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Authors and funding
8 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundBuruli ulcer (BU), one of 17 neglected tropical diseases, is a debilitating skin and soft tissue infection caused by Mycobacterium ulcerans. In tropical Africa, changes in land use and proximity to water have been associated with the disease. This study presents the first analysis of BU at the village level in southwestern Ghana, where prevalence rates are among the highest globally, and explores fine and medium-scale associations with land cover by comparing patterns both within BU clusters and surrounding landscapes. METHODOLOGY/PRINCIPAL
findingsWe obtained 339 hospital-confirmed BU cases in southwestern Ghana between 2007 and 2010. The clusters of BU were identified using spatial scan statistics and the percentages of six land cover classes were calculated based on Landsat and Rapid Eye imagery for each of 154 villages/towns. The association between BU prevalence and each land cover class was calculated using negative binomial regression models. We found that older people had a significantly higher risk for BU after considering population age structure. BU cases were positively associated with the higher percentage of water and grassland surrounding each village, but negatively associated with the percent of urban. The results also showed that BU was clustered in areas with high percentage of mining activity, suggesting that water and mining play an important and potentially interactive role in BU occurrence. CONCLUSIONS/SIGNIFICANCE: Our study highlights the importance of multiple land use changes along the Offin River, particularly mining and agriculture, which might be associated with BU disease in southwestern Ghana. Our study is the first to use both medium- and high-resolution imagery to assess these changes. We also show that older populations (≥ 60 y) appear to be at higher risk of BU disease than children, once BU data were weighted by population age structures.
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