ArticleJournal of child and adolescent psychopharmacology2015
Impact of Gender, Age at Onset, and Lifetime Tic Disorders on the Clinical Presentation and Comorbidity Pattern of Obsessive-Compulsive Disorder in Children and Adolescents.
Article in Journal of child and adolescent psychopharmacology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.
- Executive functioning in adolescents with internalizing disorders: a systematic review.European child & adolescent psychiatry · 2026Pooled it
- Unraveling Gender Differences in Obsessive-Compulsive Disorder: A Focus on Key Micronutrients.Cureus · 2025Article
- Study on symptom dimensions and clinical characteristics in patients with obsessive-compulsive disorder.Revista da Associacao Medica Brasileira (1992) · 2024Article
- Disorder-specific cingulo-opercular network hyperconnectivity in pediatric OCD relative to pediatric anxiety.Psychological medicine · 2023Article
- Lifetime Prevalence, Predictors and Comorbidities of Tic Disorders: A Population-Based Survey of Children and Adolescents in Iran.Child psychiatry and human development · 2022Article
- Irritability, Defiant and Obsessive-Compulsive Problems Development from Childhood to Adolescence.Journal of youth and adolescence · 2022Article
- The OCI-CV-R: A Revision of the Obsessive-Compulsive Inventory - Child Version.Journal of anxiety disorders · 2022Article
- Phenomenology of obsessive-compulsive disorder in children and adolescents: Sample from a tertiary care center in Istanbul, Turkey.World journal of methodology · 2022Article
- Developmental Trajectories of Pediatric Obsessive-Compulsive Symptoms.Research on child and adolescent psychopathology · 2021Article
- Cognitive Control in Pediatric Obsessive-Compulsive and Anxiety Disorders: Brain-Behavioral Targets for Early Intervention.Biological psychiatry · 2021Review
- A Neurocognitive Comparison of Pediatric Obsessive-Compulsive Disorder and Trichotillomania (Hair Pulling Disorder).Journal of abnormal child psychology · 2020Article
- Obsessive-compulsive disorder in children and adolescents: epidemiology, diagnosis and management.Translational pediatrics · 2020Review
- Diagnostic Issues in Early-Onset Obsessive-Compulsive Disorder and their Treatment Implications.Current neuropharmacology · 2019Review
- [A review on the management of tic disorders in children: psychoeducation and behavioral intervention].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2018Review
- Gender disparity in pediatrics: a review of the current literature.Italian journal of pediatrics · 2018Review
- Obsessive-Compulsive Disorder in a 19-Year-Old Female Adolescent With Turner Syndrome.Journal of clinical medicine research · 2017Article
- Clinical Profile and Comorbidity of Obsessive-Compulsive Disorder among Children and Adolescents: A Cross-Sectional Observation in Bangladesh.Psychiatry journal · 2016Article
Corrections and comments
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Authors and funding
8 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundObsessive-compulsive disorder (OCD) is a heterogeneous disorder; therefore, there is a need for identifying more homogeneous subtypes. This study aimed to examine the clinical characteristics and comorbidity pattern of a large sample of pediatric OCD subjects, and to examine the impact of gender, age at onset, and lifetime tic disorders on the clinical presentation and comorbidity pattern.
methodsA total of 110 children and adolescents diagnosed with OCD were assessed using the Kiddle Schedule for Affective Disorders and Schizophrenia for School Age Children-Present and Lifetime Version (K-SADS-PL) for psychiatric comorbidity, and a clinical data form was filled out. The cutoff for differentiating prepubertal from adolescent onset was 11 years of age.
resultsA total of 83.6% of the subjects had at least one comorbid psychiatric disorder. Oppositional defiant disorder and contamination/somatic obsessions were significantly higher in males (p=0.036 and p=0.03, respectively) than in females. Depressive disorders and religious obsessions were significantly higher in the adolescent-onset group (p=0.02, p=0.05, respectively) whereas disruptive behavior disorders were higher in the prepubertal-onset group (p=0.037). Disruptive behavior disorders were significantly more frequent in the tic (+) group than in tic (-) group (p=0.021).
conclusionsThere were differences in the comorbidity pattern and clinical expression between genders and between prepubertal and adolescent-onset cases. Findings of this study supported the introduction of tic-related OCD as a specifier in Diagnostic and Statistical Manual of Mental Disorders, 5th ed. (DSM-5), and the necessity of a detailed assessment of other psychiatric disorders in youth with OCD.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.