Evidence map›Paper›PMID 26090691›Full record

ArticleEnvironmental health perspectives2016

Associations of Pregnancy Outcomes and PM2.5 in a National Canadian Study.

David M Stieb, Li Chen, Bernardo S Beckerman, Michael Jerrett, Daniel L Crouse, D Walter Rasugu Omariba, Paul A Peters, Aaron van Donkelaar, Randall V Martin, Richard T Burnett and 4 more

Abstract read
In one paragraph

Article in Environmental health perspectives, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Maternal fine particulate matter (PMEnvironmental science and pollution research international · 2019
    Pooled it
  5. Review
  6. Article
  7. Exposure to low concentrations of PMBMC public health · 2025
    Article
  8. Review
  9. Association Between Individual Air Pollution (PMJournal of Korean medical science · 2024
    Observational
  10. Article
  11. Article
  12. Article
  13. Synergic effects of PMJournal of exposure science & environmental epidemiology · 2023
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Ambient air pollution and inflammatory effects in a Canadian pregnancy cohort.Environmental epidemiology (Philadelphia, Pa.) · 2021
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

David M StiebPopulation Studies Division, Health Canada, Vancouver, British Columbia, Canada.
Li Chen
Bernardo S Beckerman
Michael Jerrett
Daniel L Crouse
D Walter Rasugu Omariba
Paul A Peters
Aaron van Donkelaar
Randall V Martin
Richard T Burnett
Nicolas L Gilbert
Michael Tjepkema
Shiliang Liu
Rose M Dugandzic

Funding

Air pollution and risk of incident hypertension and diabetes in U.S. black womenR01ES019573 · NIEHS · BOSTON UNIVERSITY MEDICAL CAMPUS · PI COOGAN, PATRICIA F · 2011 to 2015
$2.4M
NIEHS NIH HHS 5R01ES019573-04NIEHS NIH HHS R01 ES019573PHS HHS 200-2010-37394
6 · The paper itself

Abstract

backgroundNumerous studies have examined associations between air pollution and pregnancy outcomes, but most have been restricted to urban populations living near monitors.

objectivesWe examined the association between pregnancy outcomes and fine particulate matter in a large national study including urban and rural areas.

methodsAnalyses were based on approximately 3 million singleton live births in Canada between 1999 and 2008. Exposures to PM2.5 (particles of median aerodynamic diameter ≤ 2.5 μm) were assigned by mapping the mother's postal code to a monthly surface based on a national land use regression model that incorporated observations from fixed-site monitoring stations and satellite-derived estimates of PM2.5. Generalized estimating equations were used to examine the association between PM2.5 and preterm birth (gestational age < 37 weeks), term low birth weight (< 2,500 g), small for gestational age (SGA; < 10th percentile of birth weight for gestational age), and term birth weight, adjusting for individual covariates and neighborhood socioeconomic status (SES).

resultsIn fully adjusted models, a 10-μg/m(3) increase in PM2.5 over the entire pregnancy was associated with SGA (odds ratio = 1.04; 95% CI 1.01, 1.07) and reduced term birth weight (-20.5 g; 95% CI -24.7, -16.4). Associations varied across subgroups based on maternal place of birth and period (1999-2003 vs. 2004-2008).

conclusionsThis study, based on approximately 3 million births across Canada and employing PM2.5 estimates from a national spatiotemporal model, provides further evidence linking PM2.5 and pregnancy outcomes.

Indexed as

Infant, Low Birth WeightInfant, Small for Gestational AgeMaternal ExposureAdolescentAdultAir PollutantsCanadaFemaleHumansInfant, NewbornMaleParticle SizeParticulate MatterPregnancyPremature BirthRural PopulationAir PollutantsParticulate Matter

Identifiers

PMID26090691
PMCPMC4749076

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.