Evidence map›Paper›PMID 26090480›Full record

ReviewJournal of immunology research2015

Treatment of Bullous Systemic Lupus Erythematosus.

Lihua Duan, Liying Chen, Shan Zhong, Ying Wang, Yan Huang, Yan He, Jie Chen, Guixiu Shi

Open access · goldAbstract readReview
In one paragraph

Review in Journal of immunology research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.2field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 46 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Current rheumatology reviews · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. [Young woman with new vesiculobullous eruptions].Dermatologie (Heidelberg, Germany) · 2023
    Article
  9. Article
  10. Bullous systemic lupus erythematosus in females.International journal of women's dermatology · 2022
    Review
  11. Article
  12. Article
  13. Article
  14. Vesiculobullous diseases in relation to lupus erythematosus.Clinical, cosmetic and investigational dermatology · 2019
    Article
  15. Crusted lesions on the face of a child.Pediatric dermatology · 2018
    Article
  16. Article
  17. [Systemic lupus erythematosus : Unusual cutaneous manifestations].Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete · 2016
    Review
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Lihua DuanDepartment of Rheumatology and Clinical Immunology, The First Hospital of Xiamen University, Xiamen 361003, China.ORCID 0000-0002-1631-4675
Liying ChenDepartment of Rheumatology and Clinical Immunology, The First Hospital of Xiamen University, Xiamen 361003, China.
Shan ZhongDepartment of Pathology, The First Hospital of Xiamen University, Xiamen 361003, China.
Ying WangDepartment of Rheumatology and Clinical Immunology, The First Hospital of Xiamen University, Xiamen 361003, China.
Yan HuangDepartment of Rheumatology and Clinical Immunology, The First Hospital of Xiamen University, Xiamen 361003, China.
Yan HeDepartment of Rheumatology and Clinical Immunology, The First Hospital of Xiamen University, Xiamen 361003, China.
Jie ChenDepartment of Immunology, College of Medicine, Xiamen University, Xiamen 361102, China.
Guixiu ShiDepartment of Rheumatology and Clinical Immunology, The First Hospital of Xiamen University, Xiamen 361003, China.
First Affiliated Hospital of Xiamen University · CNXiamen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bullous systemic lupus erythematosus (BSLE) is an autoantibody-mediated vesiculobullous disease in patients with SLE. Autoimmunity in BSLE is characterized by the presence of circulating anti-type VII collagen antibodies. BSLE patients often present with multiple, tense, clear fluid-filled vesicles and bullae overlying erythematous edematous plaques. Skin biopsy from BSLE patients shows subepidermal bullae with numerous neutrophils and only occasional eosinophils. Furthermore, immunofluorescence examination showed linear deposition of lgG, lgA, C3, and C1q along the basement membrane zone. BSLE patients with corticosteroids treatment constantly do not receive a marked improvement, while dapsone generally dramatically improved the skin condition. Recently, it has been reported that quite a few cases of BSLE were successfully treated with other immune suppressive drugs. Therefore, a comprehensive review of the treatment of BSLE would be beneficial to cure the disease.

Indexed as

AutoantibodiesAutoimmunityHumansImmunosuppressive AgentsLupus Erythematosus, SystemicSkinAutoantibodiesImmunosuppressive Agents

Identifiers

PMID26090480
PMCPMC4451988
OpenAlexW1598610184

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.