ArticleBioMed research international2015
Swimming Activity Prevents the Unloading Induced Loss of Bone Mass, Architecture, and Strength in Rats.
Article in BioMed research international, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 26 citations in OpenAlex.
- Description and Analysis of Horse Swimming Strategies in a U-Shaped Pool.Animals : an open access journal from MDPI · 2025Article
- Impact of Long-Term Swimming Exercise on Rat Femur Bone Quality.Biomedicines · 2023Article
- Physiotherapeutic Protocol and ZnO Nanoparticles: A Combined Novel Treatment Program against Bacterial Pyomyositis.Biology · 2022Article
- Effects of Different Types of Mechanical Loading on Trabecular Bone Microarchitecture in Rats.Journal of bone metabolism · 2021Article
- Kinematic Analysis During Straight Line Free Swimming in Horses: Part 1 - Forelimbs.Frontiers in veterinary science · 2021Article
- Effects of mild hyperbaric oxygen on osteoporosis induced by hindlimb unloading in rats.Journal of bone and mineral metabolism · 2020Article
- Protective Effects of Controlled Mechanical Loading of Bone in C57BL6/J Mice Subject to Disuse.JBMR plus · 2020Article
- Dipeptidyl peptidase-4 inhibitors and aerobic exercise synergistically protect against liver injury in ovariectomized rats.Physiological reports · 2019Article
- Compromised Exercise Capacity and Mitochondrial Dysfunction in the Osteogenesis Imperfecta Murine (oim) Mouse Model.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2019Article
- Influence of High-Fat Diet on Bone Tissue: An Experimental Study in Growing Rats.The journal of nutrition, health & aging · 2017Article
- Effects of Hindlimb Unweighting on MBP and GDNF Expression and Morphology in Rat Dorsal Root Ganglia Neurons.Neurochemical research · 2016Article
- Chronic Psychosocial Stress Impairs Bone Homeostasis: A Study in the Social Isolation Reared Rat.Frontiers in pharmacology · 2016Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We investigated whether swimming activity associated with a three-week period of hypoactivity could prevent the deleterious effects of disuse on the tibias of tail-suspended rats. Forty Wistar rats were divided into five groups: (HS) permanently hindlimb suspension rats; (HS + Swim) rats submitted to unloading interrupted by swimming exercise; (HS + WB) hindlimb suspension rats with interruption for regular weight bearing for the same length of time as the HS+Swim rats; (Control) control rats that were allowed regular cage activities; and (Control + Swim) control rats that underwent swimming exercise. At the end of the experiment, bone mineral density, bone strength, and trabecular quantification were analyzed. The hindlimb-suspended rats exhibited bone quality loss (significant decrease in BMD, bone strength, and deterioration of trabecular and cortical bone architecture; decrease in BV/TV, TbN, TbTh, ConnD, CtV, and CtTh; and increase in TbSp) when compared to control rats. In contrast, trained rats showed a significant increase of 43% in bone mass, 29% in bone strength, 58% in trabecular thickness, 85% in bone volume, 27% in trabeculae number, and 30% in cortical volume, when compared to the hindlimb-suspended rats. We conclude that swimming activity not only ameliorates but also fully prevents the deleterious effects on bone quality in osteopenic rats.
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