ReviewJournal of movement disorders2015
(123)I-Metaiodobenzylguanidine Myocardial Scintigraphy in Lewy Body-Related Disorders: A Literature Review.
Review in Journal of movement disorders, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
37 citing papers in PubMed, 2 syntheses or guidelines pooled it, 60 citations in OpenAlex.
- Neuroimaging Findings of Psychosis in Alzheimer's Disease: A Systematic Review.Brain and behavior · 2025Pooled it
- Management of Hypertension and Blood Pressure Dysregulation in Patients with Parkinson's Disease-a Systematic Review.Current hypertension reports · 2021Pooled it
- On the Utility of MIBG SPECT/CT in Evaluating Cardiac Sympathetic Dysfunction in Lewy Body Diseases.PloS one · 2016Trial
- Clinical Significance of Thyroid 123I- Meta-Iodobenzylguanidine Uptake in Parkinson's Disease.Journal of movement disorders · 2026Article
- Clinical correlates of data-driven subtypes of deep gray matter atrophy and dopamine availability in early Parkinson's disease.NPJ Parkinson's disease · 2025Article
- Value of multi-parameterEJNMMI research · 2025Article
- Gastric emptying time and its correlation with cardiac MIBG in body-first and brain-first subtype Parkinson's disease.Journal of neurology · 2024Article
- Conventional magnetic resonance imaging key features for distinguishing pathologically confirmed corticobasal degeneration from its mimics: a retrospective analysis of the J-VAC study.Neuroradiology · 2024Article
- Blunted tachycardia and cardiac sympathetic denervation in isolated rapid eye movement sleep behavior disorder.BMC neurology · 2024Article
- Cardiac 123I-Metaiodobenzylguanidine (MIBG) Scintigraphy in Parkinson's Disease: A Comprehensive Review.Brain sciences · 2023Review
- Optimal Protocol and Clinical Usefulness ofNuclear medicine and molecular imaging · 2023Article
- Sudden cardiac death in synucleinopathies.Journal of neuropathology and experimental neurology · 2023Article
- Differentiating Dementia with Lewy Bodies from Alzheimer's Disease Using the Fall Risk Evaluation Questionnaire.Internal medicine (Tokyo, Japan) · 2022Article
- Cardiac Alpha-Synuclein Is Present in Alpha-Synucleinopathies.Journal of Parkinson's disease · 2022Article
- Cardiac Autonomic Dysfunction Is Associated with Severity of REM Sleep without Atonia in Isolated REM Sleep Behavior Disorder.Journal of clinical medicine · 2021Article
- Uniformity of cardiacJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021Article
- Myocardial Sympathetic Innervation Imaging with MIBG in Dementia with Lewy Bodies.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021Article
- CardiacJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2021Article
- Lewy Body Dementias: A Coin with Two Sides?Behavioral sciences (Basel, Switzerland) · 2021Review
- Identification of BAG2 and Cathepsin D as Plasma Biomarkers for Parkinson's Disease.Clinical and translational science · 2021Observational
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Lewy body-related disorders are characterized by the presence of Lewy bodies and Lewy neurites, which have abnormal aggregations of α-synuclein in the nigral and extranigral areas, including in the heart. (123)I-metaiodobenzylguanidine (MIBG) scintigraphy is a well-known tool to evaluate cardiac sympathetic denervation in the Lewy body-related disorders. MIBG scintigraphy showed low uptake of MIBG in the Lewy body-related disorders, including Parkinson's disease, dementia with Lewy bodies, pure autonomic failure and rapid eye movement sleep behavior disorder. This review summarizes previous results on the diagnostic applications of MIBG scintigraphy in Lewy body-related disorders.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.