Evidence map›Paper›PMID 26088442›Full record

ArticleDiabetologia2015

Risk factors for atrial fibrillation in type 2 diabetes: report from the Swedish National Diabetes Register (NDR).

Björn Zethelius, Soffia Gudbjörnsdottir, Björn Eliasson, Katarina Eeg-Olofsson, Ann-Marie Svensson, Jan Cederholm

Open access · bronzeAbstract read
PubMed Publisher
In one paragraph

Article in Diabetologia, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 39 citations in OpenAlex.

  1. Review
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  7. Observational
  8. Article
  9. Incidence and Risk Assessment for Atrial Fibrillation at 5 Years: Hypertensive Diabetic Retrospective Cohort.International journal of environmental research and public health · 2020
    Article
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  12. Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Björn ZetheliusDepartment of Public Health and Caring Sciences/Geriatrics, Uppsala University, Uppsala Science Park, 75185, Uppsala, Sweden. bjorn.zethelius@pubcare.uu.se.
Soffia GudbjörnsdottirDepartment of Medicine, Sahlgrenska University Hospital, University of Gothenburg, Gothenburg, Sweden.
Björn EliassonDepartment of Medicine, Sahlgrenska University Hospital, University of Gothenburg, Gothenburg, Sweden.
Katarina Eeg-OlofssonDepartment of Medicine, Sahlgrenska University Hospital, University of Gothenburg, Gothenburg, Sweden.
Ann-Marie SvenssonDepartment of Medicine, Sahlgrenska University Hospital, University of Gothenburg, Gothenburg, Sweden.
Jan CederholmDepartment of Public Health and Caring Sciences/Family Medicine and Preventive Medicine, Uppsala University, Uppsala, Sweden.
Sahlgrenska University Hospital · SEUniversity of Gothenburg · SEUppsala University · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aims/hypothesisAtrial fibrillation (AF) is more frequent in patients with diabetes than in the general population. However, characteristics contributing to AF risk in diabetes remain speculative.

methodsObservational study of 83,162 patients with type 2 diabetes, aged 30-79 years, with no baseline AF, 17% had history of cardiovascular disease (CVD) and 3.3% history of congestive heart failure (CHF), followed up for development of AF during mean 6.8 years from 2005-2007 to 2012. A subgroup of 67,780 patients without history of CVD or CHF was also analysed.

resultsUsing Cox regression, cardiovascular risk factors associated with risk for AF were updated mean BMI (HR 1.31 per 5 kg/m(2)) or obesity (HR 1.51), updated mean systolic BP (SBP; HR 1.13 per 10 mmHg) or hypertension (HR 1.71), and cumulative microalbuminuria (HR 1.21), p < 0.001 for all analyses. Male sex, increasing age and height were also significant predictors. HRs were 1.76 for a history of CHF and 2.56 for in-study CHF, while 1.32 for history of CVD and 1.38 for in-study CHD (p < 0.001). Among patients without history of CVD or CHF, significant predictors were similarly BMI, SBP, and cumulative microalbuminuria and CHF. The risk of AF differed in the subgroups achieving or not achieving a target BP < 140/85 mmHg. The HRs for AF were (per 10 mmHg increase) 0.88 and 1.24, respectively. CONCLUSIONS/

interpretationThe modifiable risk factors high BP, high BMI and albuminuria were strongly associated with AF in type 2 diabetes. CVD, advancing age and height were also associated with AF in type 2 diabetes.

Indexed as

AdultAgedAge FactorsAlbuminuriaAtrial FibrillationBlood PressureDiabetes Mellitus, Type 2FemaleHumansHypertensionMaleMiddle AgedRegistriesRisk FactorsSex FactorsSwedenAtrial fibrillationCardiovascular diseasesDiabetes mellitusMyocardial infarctionRegistry

Identifiers

PMID26088442
OpenAlexW2228533831

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.