Evidence map›Paper›PMID 26088149›Full record

ArticleBurns : journal of the International Society for Burn Injuries2015

Timing of early excision and grafting following burn in sub-Saharan Africa.

Jared R Gallaher, Stephen Mjuweni, Mansi Shah, Bruce A Cairns, Anthony G Charles

Abstract read
In one paragraph

Article in Burns : journal of the International Society for Burn Injuries, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Article
  2. Observational
  3. Article
  4. Article
  5. The treatment effect of operative intervention for flame versus scald burns in resource-limited settings.Burns : journal of the International Society for Burn Injuries · 2024
    Article
  6. Article
  7. Article
  8. Burns among adults in a major Malawian burn unit: epidemiology and factors associated with prolonged hospital stay.Malawi medical journal : the journal of Medical Association of Malawi · 2023
    Article
  9. The effect of COVID-19 on burn management and outcomes in a resource-limited setting.Burns : journal of the International Society for Burn Injuries · 2022
    Article
  10. Article
  11. Article
  12. Article
  13. Palliation, end-of-life care and burns; concepts, decision-making and communication - A narrative review.African journal of emergency medicine : Revue africaine de la medecine d'urgence · 2020
    Review
  14. Early Excision and Grafting in Burns: An Experience in a Tertiary Care Industrial Hospital of Eastern India.Indian journal of plastic surgery : official publication of the Association of Plastic Surgeons of India · 2019
    Article
  15. Article
  16. Article
  17. A systematic review of burn injuries in low- and middle-income countries: Epidemiology in the WHO-defined African Region.African journal of emergency medicine : Revue africaine de la medecine d'urgence · 2017
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jared R GallaherDepartment of Surgery, University of North Carolina, School of Medicine, CB# 7228, Chapel Hill, NC, USA.
Stephen MjuweniDepartment of Surgery, Kamuzu Central Hospital, Lilongwe, Malawi.
Mansi ShahDepartment of Surgery, University of North Carolina, School of Medicine, CB# 7228, Chapel Hill, NC, USA.
Bruce A CairnsNorth Carolina Jaycee Burn Center, Department of Surgery, University of North Carolina, School of Medicine, CB# 7600, Chapel Hill, NC, USA.
Anthony G CharlesDepartment of Surgery, University of North Carolina, School of Medicine, CB# 7228, Chapel Hill, NC, USA; Department of Surgery, Kamuzu Central Hospital, Lilongwe, Malawi; North Carolina Jaycee Burn Center, Department of Surgery, University of North Carolina, School of Medicine, CB# 7600, Chapel Hill, NC, USA. Electronic address: anthchar@med.unc.edu.

Funding

TRAUMA RESEARCH FELLOWSHIPT32GM008450 · NIGMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Bruce A Cairns, Anthony G Charles · 1992 to 2026
$3.8M
NIGMS NIH HHS T32 GM008450
6 · The paper itself

Abstract

backgroundThis study sought to establish appropriate timing of burn wound excision and grafting in a resource-poor setting in sub-Saharan Africa.

methodsAll burn patients (905 patients) admitted to Kamuzu Central Hospital (KCH) Burn Unit in Lilongwe, Malawi over three years (2011-2014) were studied.

results275 patients (30%) had an operation during their admission. In patients who received an operation, median age was 5 years (IQR, 2.7-19) and median total body surface area burn was 15% (IQR, 8-25). 91 patients (33%) had early excision (≤5 days) and 184 patients (67%) had late excision (>5 days). Mortality was significantly greater in the early group (25.3% vs. 9.2%, p=0.001). Controlling for total body surface area burn and age, the adjusted predictive probability of mortality were 0.256 (CI 0.159-0.385) and 0.107 (CI 0.062-0.177) if operated ≤5 and >5 days, respectively (p=0.0114). The odds ratio for mortality if operated >5 days is 0.34 (CI 0.15-0.79, p<0.000).

conclusionsEarly excision and grafting in a resource-poor area in sub-Saharan Africa is associated with a significant increase in mortality. Delaying the timing of early excision and grafting of burn patients in a resource-poor setting past burn day 5 may confer a survival advantage.

Indexed as

RegistriesAdolescentAdultAfrica South of the SaharaAgedAged, 80 and overBody Surface AreaBurnsChildChild, PreschoolCohort StudiesEarly Medical InterventionFemaleHealth ResourcesHumansInfantBurn care in MalawiBurns in AfricaEarly excision and graftingGlobal surgeryOperative timingTiming of burn excision

Identifiers

PMID26088149
PMCPMC5171218

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.