Evidence map›Paper›PMID 26087651›Full record

ArticlePediatric rheumatology online journal2015

Practice patterns and approach to kidney biopsy in lupus: a collaboration of the Midwest Pediatric Nephrology Consortium and the Childhood Arthritis and Rheumatology Research Alliance.

Scott E Wenderfer, Jerome C Lane, Ibrahim F Shatat, Emily von Scheven, Natasha M Ruth

Open access · goldAbstract readMulticenter Study
In one paragraph

Article in Pediatric rheumatology online journal, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Review
  3. New Insights on Childhood Lupus Nephritis.International journal of nephrology and renovascular disease · 2025
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Scott E WenderferPediatric Nephrology, Texas Children's Hospital, Baylor College of Medicine, Houston, TX, USA. wenderfe@bcm.edu.
Jerome C LanePediatric Nephrology, Ann and Robert H. Lurie Children's Hospital of Chicago, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA. j-lane@northwestern.edu.
Ibrahim F ShatatPediatric Nephrology, Medical University of South Carolina Children's Hospital, Charleston, SC, USA. shatat@musc.edu.
Emily von SchevenPediatric Rheumatology, University of California San Francisco, San Francisco, CA, USA. evonsche@peds.ucsf.edu.
Natasha M RuthPediatric Rheumatology, Medical University of South Carolina Children's Hospital, Charleston, SC, USA. ruthn@musc.edu.
Medical University of South Carolina · USNorthwestern University · USTexas Children's Hospital · USUniversity of California, San Francisco · US

Funding

LCenter for Clinical and Translational Science and TrainingUL1TR001425 · NCATS · UNIVERSITY OF CINCINNATI · PI HEUBI, JAMES E., KISSELA, BRETT M · 2015 to 2024
$37.5M
Cincinnati Center for Clinical and Translational Sciences and TrainingUL1TR000077 · NCATS · UNIVERSITY OF CINCINNATI · PI HEUBI, JAMES E. · 2012 to 2014
$9.9M
CARRA: Accelerating Toward an Evidence Based Culture in Pediatric RheumatologyRC2AR058934 · NIAMS · DUKE UNIVERSITY · PI ILOWITE, NORMAN T, SANDBORG, CHRISTY IRENE · 2009 to 2010
$6.8M
Immunoglobulin Receptors and Immune Complex Processing in the KidneyK08DK081663 · NIDDK · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI WENDERFER, SCOTT E · 2009 to 2013
$694k
NCATS NIH HHS UL1 TR000077NCATS NIH HHS UL1 TR001425NIAMS NIH HHS RC2 AR058934NIAMS NIH HHS RC2AR058934NIDDK NIH HHS DK081663NIDDK NIH HHS K08 DK081663
6 · The paper itself

Abstract

backgroundThere is no clear consensus regarding optimal indications or timing of initial or repeat kidney biopsy in the management of pediatric systemic lupus erythematosus (pSLE).

methodsA web-based survey was designed to assess current practice patterns among pediatric nephrologists and pediatric rheumatologists and distributed to members of Midwest Pediatric Nephrology Consortium (MWPNC) and Childhood Arthritis and Rheumatology Research Alliance (CARRA).

resultsRespondents included 111 rheumatologists and 71 nephrologists from 65 and 34 centers, respectively. Numbers of years in sub-specialty practice were comparable. Rheumatologists and nephrologists frequently collaborate in the care of children with lupus nephritis (LN). More than 90% of respondents refer patients to each either other after diagnosing LN. Over 60% describe shared decision making regarding when to perform kidney biopsy and how to interpret biopsy findings. Many pediatric nephrologists consider biopsy to be of higher risk for complication in pSLE and alter their standard pre-or post-biopsy management.

conclusionsIt is uncommon for pediatric nephrologists to manage LN without input from pediatric rheumatologists and vice versa. Consensus exists between specialties in general, and practice differences that exist occur between individual physicians rather than between specialties. A systematic approach to biopsy may result in improved health related outcomes in pSLE.

Indexed as

Practice Patterns, Physicians'BiopsyChildCooperative BehaviorData CollectionHumansKidneyLupus Erythematosus, SystemicMidwestern United StatesNephritisNephrologyRheumatologySocieties, MedicalSpecialization

Identifiers

PMID26087651
PMCPMC4474548
OpenAlexW1847058334

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.