ArticlePloS one2015
Significant Reductions in Mortality in Hospitalized Patients with Systemic Lupus Erythematosus in Washington State from 2003 to 2011.
Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- Identification of key programmed cell death genes-necroptosis-related genes in systemic lupus erythematosus.Clinical and experimental medicine · 2026Article
- Magnitude and Impact of Hallucinations in Tabular Synthetic Health Data on Prognostic Machine Learning Models: Validation Study.Journal of medical Internet research · 2025Article
- Impact of severe infections in SLE: an observational study from the Spanish national registry.Lupus science & medicine · 2022Observational
- Trends in Hospital Admissions and Death Causes in Patients with Systemic Lupus Erythematosus: Spanish National Registry.Journal of clinical medicine · 2021Article
- Mortality Among Hospitalized Individuals With Systemic Lupus Erythematosus in the US Between 2006 and 2016.Arthritis care & research · 2021Article
- Childhood-Onset Systemic Lupus Erythematosus: Southeast Asian Perspectives.Journal of clinical medicine · 2021Review
- Reasons for Hospitalization and In-Hospital Mortality in Adult Systemic Lupus Erythematosus.ACR open rheumatology · 2020Article
- The Epidemiology and Outcomes of Mental Disorders in Critically Ill Patients With Systemic Lupus Erythematosus: A Population-Based Study.Journal of clinical medicine research · 2020Article
- Epidemiology and outcomes of sepsis among hospitalizations with systemic lupus erythematosus admitted to the ICU: a population-based cohort study.Journal of intensive care · 2020Article
- All-cause hospitalizations in systemic lupus erythematosus from a single medical center in Israel.Rheumatology international · 2018Article
- GnRH Antagonist Improves Pubertal Cyclophosphamide-Induced Long-Term Testicular Injury in Adult Rats.International journal of endocrinology · 2018Article
- Cardiovascular Disease Prevention Counseling Program for Systemic Lupus Erythematosus Patients.Arthritis care & research · 2017Article
- Effective Self-Management Interventions for Patients With Lupus: Potential Impact of Peer Mentoring.The American journal of the medical sciences · 2017Review
- Article
- Article
Corrections and comments
- Erratum issued
Authors and funding
5 authors.
Funding
Abstract
backgroundSystemic lupus erythematosus (SLE or lupus) is an autoimmune multisystem disease. While a complete understanding of lupus' origins, mechanisms, and progression is not yet available, a number of studies have demonstrated correlations between disease prevalence and severity, gender, and race. There have been few population based studies in the United States.
objectivesTo assess temporal changes in demographics and hospital mortality of patients with lupus in Washington State from 2003 to 2011. STUDY
designThis study used data from the Healthcare Cost and Utilization Project (HCUP), a patient information database, and data from the Washington State census to study a group of patients in the state. Lupus hospitalizations were defined as any hospitalization with an ICD-9-CM diagnosis code for systemic lupus erythematosus. Regression analysis was used to assess the effect of calendar time on demographics and hospital outcomes.
resultsThere were a total of 18,905 patients in this study with a diagnostic code for lupus. The mean age of the group was 51.5 years (95% CI: 50.6-52.3) in 2003 and 51.3 years (95% CI: 50.6-52.0) in 2011. The population was 88.6% female. Blacks were 2.8 times more likely to have a lupus hospitalization than whites when compared to the Washington population. While hospital mortality decreased during this eight year period (3.12% in 2003 to 1.28% in 2011, p=0.001) hospital length of stay remained statistically unchanged at an average of 4.9 days during that eight year period. We found a significant decrease in annual hospital mortality over the study period [odds ratio(OR): 0.92 per year, 95% CI 0.88-0.96, P<0.001]. Hospital mortality was higher in males (2.6% male death to 1.8% female death).
conclusionsIn this large group of hospitalized lupus patients in Washington, hospital length of stay remained relatively stable over time but hospital mortality decreased by over 50% over the eight year study period.
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