ArticlePloS one2015
Value of Lung Ultrasonography in the Diagnosis and Outcome Prediction of Pediatric Community-Acquired Pneumonia with Necrotizing Change.
Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.
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Who cites it
28 citing papers in PubMed, 1 synthesis or guideline pooled it, 75 citations in OpenAlex.
- Factors Associated With Pneumonia Severity in Children: A Systematic Review.Journal of the Pediatric Infectious Diseases Society · 2018Pooled it
- Clinical utility of lung ultrasound in differentiating and monitoring complicated pediatric pneumonia: a prospective diagnostic accuracy study.Italian journal of pediatrics · 2026Article
- Role of Thoracic Ultrasound in the Management of Parapneumonic Effusion According to the Proposed Algorithm/Classification in Pediatric Pneumonia: A Single Center Study.Health science reports · 2026Article
- Diagnostic performance of lung ultrasound for detecting lung necrosis in children with community-acquired pneumonia.Pediatric research · 2026Article
- Oral pentoxifylline as a novel adjunct to standard therapy in pediatric community-acquired pneumonia: a randomized controlled trial.Pediatric research · 2026Article
- Ten Questions on Using Lung Ultrasonography to Diagnose and Manage Pneumonia in Hospital-at-Home Model: Part III-Synchronicity and Foresight.Diagnostics (Basel, Switzerland) · 2026Review
- Necrotizing Pneumonia in a Vaccinated Child: A Rare Complication of Viral and Bacterial Co-infection.Cureus · 2025Article
- [Pneumonia in childhood and adolescence].Radiologie (Heidelberg, Germany) · 2025Review
- A Comprehensive Review of Pediatric Necrotizing Pneumonia.Children (Basel, Switzerland) · 2025Review
- Echoes of change: lung ultrasound revolutionizing neonatal and pediatric respiratory care.Pediatric radiology · 2025Review
- A complex case of necrotizing pneumonia and parapneumonic effusion in a healthy 20-month-old child: Successful management with video-assisted thoracoscopic surgery and chest tube placement.Radiology case reports · 2024Article
- Management of pediatric pleural empyema: a national survey of pediatric surgeons in Brazil.Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia · 2024Article
- Necrotizing Pneumonia in Children: Early Recognition and Management.Journal of clinical medicine · 2023Review
- Clinical Characteristics of Necrotizing Pneumonia Caused by Different Pathogens.Infection and drug resistance · 2023Article
- Development of a Nomogram for Predicting Massive Necrotizing Pneumonia in Children.Infection and drug resistance · 2023Article
- The utility of chest x-ray and lung ultrasound in the management of infants and children presenting with severe pneumonia in low-and middle-income countries: A pragmatic scoping review.Journal of global health · 2022Article
- CT findings predicting lung resection in children with complicated community-acquired pneumonia.Pediatric surgery international · 2022Article
- Necrotizing pneumonia in children: Chest computed tomography vs. lung ultrasound.Frontiers in pediatrics · 2022Article
- Lung Ultrasound in Pediatrics and Neonatology: An Update.Healthcare (Basel, Switzerland) · 2021Review
- Response to Comment on Jaworska, J. et al. Consensus on the Application of Lung Ultrasound in Pneumonia and Bronchiolitis in Children.Diagnostics (Basel, Switzerland) · 2021Article
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundLung ultrasonography has been advocated in diagnosing pediatric community-acquired pneumonia. However, its function in identifying necrotizing pneumonia, a complication, has not been explored. This study investigated the value of lung ultrasonography in diagnosing pediatric necrotizing pneumonia and its role in predicting clinical outcomes.
methodsWe retrospectively reviewed 236 children with community-acquired pneumonia who were evaluated using lung ultrasonography within 2-3 days after admission. The ultrasonographic features assessed included lung perfusion, the presence of hypoechoic lesions, and the amount of pleural effusion. Chest computed tomography was also performed in 96 patients as clinically indicated. Detailed records of clinical information were obtained.
resultsOur results showed a high correlation between the degree of impaired perfusion in ultrasonography and the severity of necrosis in computed tomography (r = 0.704). The degree of impaired perfusion can favorably be used to predict massive necrosis in computed tomography (area under the receiver operating characteristic curve, 0.908). The characteristics of impaired perfusion and hypoechoic lesions in ultrasonography were associated with an increased risk of pneumatocele formation (odds ratio (OR), 10.11; 95% CI, 2.95-34.64) and the subsequent requirement for surgical lung resection (OR, 8.28; 95% CI, 1.86-36.93). Furthermore, a longer hospital stay would be expected if moderate-to-massive pleural effusion was observed in addition to impaired perfusion in ultrasonography (OR, 3.08; 95% CI, 1.15-8.29).
conclusionLung ultrasonography is favorably correlated with chest computed tomography in the diagnosis of necrotizing pneumonia, especially regarding massive necrosis of the lung. Because it is a simple and reliable imaging tool that is valuable in predicting clinical outcomes, we suggest that ultrasonography be applied as a surrogate for computed tomography for the early detection of severe necrotizing pneumonia in children.
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