Trial reportPediatric research2015
Components of the metabolic syndrome in early childhood in very-low-birth-weight infants and term small and appropriate for gestational age infants.
Trial report in Pediatric research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 42 citations in OpenAlex.
- Association between low birth weight and impaired glucose tolerance in children: a systematic review and meta-analysis.Frontiers in pediatrics · 2024Pooled it
- Growth, metabolic markers, and cognition in 8-year old children born prematurely, follow-up of a randomized controlled trial with essential fatty acids.European journal of pediatrics · 2016Trial
- Preterm Birth, Fetal Growth Restriction and Early Postnatal Body Mass Index Normalisation Predict Adult Anthropometry.Acta paediatrica (Oslo, Norway : 1992) · 2026Article
- Childhood occasional hypertension and its association with size at birth and early growth: a population-based retrospective cohort study from China.Italian journal of pediatrics · 2025Article
- Article
- Insulin resistance prior to term age in very low birthweight infants: a prospective study.BMJ paediatrics open · 2024Observational
- Association of size for gestational age and dehydroepiandrosterone sulfate with cardiometabolic risk in central precocious puberty girls.Frontiers in endocrinology · 2023Article
- Platelets in Fetal Growth Restriction: Role of Reactive Oxygen Species, Oxygen Metabolism, and Aggregation.Cells · 2022Article
- Extreme Birth Weight and Metabolic Syndrome in Children.Nutrients · 2022Observational
- Impact of very preterm birth and post-discharge growth on cardiometabolic outcomes at school age: a retrospective cohort study.BMC pediatrics · 2021Article
- Biochemical predictors for metabolic syndrome in preterm infants according to weight ratio.Archives of endocrinology and metabolism · 2021Article
- Impact of size at birth and postnatal growth on metabolic and neurocognitive outcomes in prematurely born school-age children.Scientific reports · 2021Article
- Chemerin concentrations in infants born small for gestational age: correlations with triglycerides and parameters related to glucose homeostasis.Journal of physiology and biochemistry · 2021Article
- Small for Gestational Age Preterm Neonates Exhibit Defective GH/IGF1 Signaling Pathway.Frontiers in pediatrics · 2021Article
- Increased risk for early hypertriglyceridemia in small for gestational age preterm infants.European journal of pediatrics · 2020Article
- Does low birthweight matter?Acta paediatrica (Oslo, Norway : 1992) · 2020Article
- More Maternal Vascular Malperfusion and Chorioamnionitis in Placentas After Expectant Management vs. Immediate Delivery in Fetal Growth Restriction at (Near) Term: A Further Analysis of the DIGITAT Trial.Frontiers in endocrinology · 2019Article
- More Prevalent Prescription of Medicine for Hypertension and Metabolic Syndrome in Males from Couples Undergoing Intracytoplasmic Sperm Injection.Scientific reports · 2018Article
- Small for gestational age and obesity related comorbidities.Annals of pediatric endocrinology & metabolism · 2018Review
- IGF-I and relation to growth in infancy and early childhood in very-low-birth-weight infants and term born infants.PloS one · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTerm small-for-gestational-age (SGA) and preterm born infants have an increased prevalence of metabolic syndrome components already in childhood. Our recent study in 2-y-old very-low-birth-weight (VLBW) infants was limited by the absence of a control group of term born children. We compared the metabolic syndrome components in early childhood in VLBW and term SGA infants to term appropriate for gestational age (AGA) infants.
methodsWe included 38 VLBW children and 82 term born children (64 AGA/18 SGA). HDL cholesterol, triglycerides, glucose, and insulin were measured in blood samples taken at 1 y (term children) and 2 y (all children) of (corrected) age.
resultsAt 2 y corrected age, VLBW children have lower BMI and higher glucose level compared to AGA children. SGA children have lower BMI at 1 and 2 y of age and a high prevalence of high triglyceride levels at 1 y of age compared to AGA children. Total body fat is a significant determinant of HDL cholesterol and triglycerides and birth weight is a significant determinant of glucose at 2 y corrected age.
conclusionIn early childhood, VLBW and term SGA children already have a high prevalence of some metabolic syndrome components compared to term AGA children.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.