Evidence map›Paper›PMID 26086573›Full record

ReviewContraception2015

Endometriosis-induced changes in regulatory T cells - insights towards developing permanent contraception.

Asgerally T Fazleabas, Andrea Braundmeier, Kirstin Parkin

Abstract readReview
In one paragraph

Review in Contraception, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.3field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Asgerally T FazleabasDepartment of Obstetrics, Gynecology and Reproductive Biology, Michigan State University College of Human Medicine, MI 48824, USA. Electronic address: asgi@hc.msu.edu.
Andrea BraundmeierDepartment of Medical Microbiology, Immunology and Cell Biology, Southern Illinois University School of Medicine, IL 62702, USA.
Kirstin ParkinDepartment of Microbiology and Molecular Genetics, Michigan State University College of Human Medicine, MI 48824, USA.
Michigan State University · USSouthern Illinois University School of Medicine · US

Funding

Tissue Procurement and Cell CultureU54HD040093 · NICHD · UNIVERSITY OF ILLINOIS AT CHICAGO · PI LEACH, RICHARD E · 2002 to 2011
$13.1M
Role of microRNA in the Pathophysiology of EndometriosisR01HD083273 · NICHD · MICHIGAN STATE UNIVERSITY · PI FAZLEABAS, ASGERALLY T. · 2016 to 2020
$1.8M
NICHD NIH HHS R01 HD083273NICHD NIH HHS U54 HD040093NICHD NIH HHS U54 HD 40093
6 · The paper itself

Abstract

backgroundEndometriosis is a gynecological disorder that is associated with alterations in the immune system that contributes to its pathology as well as its associated infertility. MAIN

findingsThis brief report summarizes our findings related to the changes in T regulatory cells (Tregs) that may affect the uterine environment and impact the fertility of women and nonhuman primates with endometriosis. PRINCIPAL

conclusionTargeted therapies that could reduce Tregs within the reproductive tract may have a potential as long-lasting or permanent contraception.

Indexed as

ImmunomodulationModels, ImmunologicalAnimalsEndometriosisEndometriumFemaleHumansInfertility, FemalePapio anubisSterilization, ReproductiveT-Lymphocytes, RegulatoryEndometriosisImmune cellsInflammationUterine environment

Identifiers

PMID26086573
PMCPMC4506884
OpenAlexW2126266367

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.