Evidence map›Paper›PMID 26086431›Full record

ArticleVirology2015

Detection of non-primate hepaciviruses in UK dogs.

L M R El-Attar, J A Mitchell, H Brooks Brownlie, S L Priestnall, J Brownlie

Abstract read
In one paragraph

Article in Virology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 34 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Predominance of Canine Parainfluenza Virus andPathogens (Basel, Switzerland) · 2023
    Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Mode and tempo of human hepatitis virus evolution.Computational and structural biotechnology journal · 2019
    Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

L M R El-AttarRoyal Veterinary College, Hawkshead Lane, Hatfield, Hertfordshire AL9 7TA, UK. Electronic address: lelattar@rvc.ac.uk.
J A MitchellRoyal Veterinary College, Hawkshead Lane, Hatfield, Hertfordshire AL9 7TA, UK.
H Brooks BrownlieRoyal Veterinary College, Hawkshead Lane, Hatfield, Hertfordshire AL9 7TA, UK.
S L PriestnallRoyal Veterinary College, Hawkshead Lane, Hatfield, Hertfordshire AL9 7TA, UK.
J BrownlieRoyal Veterinary College, Hawkshead Lane, Hatfield, Hertfordshire AL9 7TA, UK.
Royal Veterinary College · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Non-primate hepacivirus (NPHV) has been identified in dogs, horses, bats and wild rodents. The presence of NPHV in dogs outside of the USA however is yet to be established. Here we describe for the first time the detection of NPHV in the UK dog population (described throughout the manuscript as CnNPHV). We examined tissues collected from dogs housed in a rehoming kennel where respiratory disease was endemic. CnNPHV RNA was detected in the tracheal tissues of 48/210 dogs by RT-PCR, and in the liver, lung and/or tracheal tissues of 12/20 dogs. The presence of CnNPHV RNA, and its tropism was confirmed by in situ hybridisation. Histopathological examination demonstrated a trend toward higher histopathological scores in CnNPHV RNA positive respiratory tissues, although, this was not statistically significant. Our findings broaden the geographic distribution and our understanding of CnNPHV. Further evidence of CnNPHV replication in canids warrants investigation.

Indexed as

AnimalsDog DiseasesDogsHepacivirusLiverLungMolecular Sequence DataRespiratory Tract InfectionsReverse Transcriptase Polymerase Chain ReactionRNA, ViralSequence Analysis, DNATracheaUnited KingdomRNA, ViralCanine hepacivirusHepacivirusesISHNPHVNPHV tropismRT-PCR

Identifiers

PMID26086431
PMCPMC7111718
OpenAlexW638794972

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.