Evidence map›Paper›PMID 26086030›Full record

ArticleCurrent opinion in psychology2015

Current Directions in Stress and Human Immune Function.

Jennifer N Morey, Ian A Boggero, April B Scott, Suzanne C Segerstrom

Abstract read
In one paragraph

Article in Current opinion in psychology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 145 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
145citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

145 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Trial
  6. Neurobiological and Anti-Inflammatory Effects of a Deep Diaphragmatic Breathing Technique Based on Neofunctional Psychotherapy: A Pilot RCT.Stress and health : journal of the International Society for the Investigation of Stress · 2024
    Trial
  7. The enhancing effects of Biobran/MGN-3, an arabinoxylan rice bran, on healthy old adults' health-related quality of life: a randomized, double-blind, placebo-controlled clinical trial.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2020
    Trial
  8. Trial
  9. Trial
  10. Article
  11. Review
  12. Observational
  13. Homo sapiens, industrialisation and the environmental mismatch hypothesis.Biological reviews of the Cambridge Philosophical Society · 2026
    Review
  14. Article
  15. Article
  16. Article
  17. The (un-)Social Brain in Isolation.Physiological research · 2025
    Review
  18. Article
  19. Article
  20. Review

85 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jennifer N MoreyUniversity of Kentucky.
Ian A BoggeroUniversity of Kentucky.
April B ScottUniversity of Kentucky.
Suzanne C SegerstromUniversity of Kentucky.

Funding

Self-Regulation, Immunological Aging, and Health in Older AdultsR01AG026307 · NIA · UNIVERSITY OF KENTUCKY · PI GOLD, BRIAN TIMOTHY, SEGERSTROM, SUZANNE C. · 2006 to 2022
$7.5M
Self-Regulation and Aging: Substrates and Health ConsequencesK02AG033629 · NIA · UNIVERSITY OF KENTUCKY · PI SEGERSTROM, SUZANNE C. · 2012 to 2016
$703k
Maintenance of Positive Affect Following Pain in Older AdultsF31AG048692 · NIA · UNIVERSITY OF KENTUCKY · PI BOGGERO, IAN ANDRES · 2014 to 2015
$84k
NIA NIH HHS F31 AG048692NIA NIH HHS K02 AG033629NIA NIH HHS R01 AG026307
6 · The paper itself

Abstract

Psychological stress has been linked empirically with dysregulation of facets of the human immune system, yet these effects are not the same in every situation or population. Recent research has made strides towards understanding risk factors for immune dysregulation as well as why these risks occur. This review discusses mechanisms and mediators underlying the stress-immune relation, the role of context in determining whether an immunologic responses to stress is adaptive versus maladaptive, and the stress-immune relation in populations including children exposed to early adversity, older adults, and individuals with clinical diagnoses. The reviewed work holds great promise for further elucidating the circumstances under which psychological stress has immunological consequences, and provides new directions for work in this field.

Identifiers

PMID26086030
PMCPMC4465119

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.