ArticleInternational journal of ophthalmology2015
Vitreous substitutes: challenges and directions.
Article in International journal of ophthalmology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Pooled it
- Chain entanglement-stabilized injectable zwitterionic hydrogel for vitreous replacement and retinal tamponade.National science review · 2026Article
- Comparison of In-Vitro and In-Vivo Drug Release of Dexamethasone/PLGA Intravitreal Implants Using Two In-Vitro Release Methods and a Rabbit Model.Molecular pharmaceutics · 2025Article
- Consensus on the Treatment of Severe Ocular Trauma and Silicone Oil-Dependent Eyes Using Foldable Capsular Vitreous Body.Journal of evidence-based medicine · 2025Article
- Injectable Dendrimer Hydrogel Delivers Melphalan in Both Conjugated and Free Forms for Retinoblastoma.Biomacromolecules · 2024Article
- Risk Factors and Management of Intraocular Pressure Elevation After Vitrectomy Combined with Silicone Oil Tamponade.International journal of general medicine · 2024Review
- Study on maintenance of eyeball morphology by foldable capsular vitreous body in severe ocular trauma.BMC ophthalmology · 2023Article
- A pilot clinical study of complex rhegmatogenous retinal detachment treatment via foldable capsular buckle scleral buckling.BMC ophthalmology · 2023Observational
- Vitreous Substitutes from Bench to the Operating Room in a Translational Approach: Review and Future Endeavors in Vitreoretinal Surgery.International journal of molecular sciences · 2023Review
- Study on the efficacy and safety of foldable capsular vitreous body in the severe retinal detachment eyes.BMC ophthalmology · 2022Article
- Vitreous Substitutes as Drug Release Systems.Translational vision science & technology · 2022Review
- Vitreous function and intervention of it with vitrectomy and other modalities.International journal of ophthalmology · 2022Article
- Peptidomimetics Therapeutics for Retinal Disease.Biomolecules · 2021Review
- Outcomes of a Foldable Capsular Vitreous Body Implantation: A Retrospective Study.Disease markers · 2021Article
- Evaluation of the long-term effect of foldable capsular vitreous bodies in severe ocular rupture.International journal of ophthalmology · 2021Article
- Vitreous function and intervention of it with vitrectomy and other modalities.International journal of ophthalmology · 2021Review
- Substitutes and Colloidal System for Vitreous Replacement and Drug Delivery: Recent Progress and Future Prospective.Polymers · 2020Review
- Effect on rabbits' intraocular structure by cross-linked hyaluronic formations as vitreous substitute.International journal of ophthalmology · 2020Article
- Study on the effectiveness and safety of Foldable Capsular Vitreous Body implantation.BMC ophthalmology · 2019Article
- Ex vivo biophysical characterization of a hydrogel-based artificial vitreous substitute.PloS one · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The natural vitreous body has a fine structure and complex functions. The imitation of the natural vitreous body by vitreous substitutes is a challenging work for both researchers and ophthalmologists. Gases, silicone oil, heavy silicone oil and hydrogels, particularly the former two vitreous substitutes are clinically widely used with certain complications. Those, however, are not real artificial vitreous due to lack of structure and function like the natural vitreous body. This article reviews the situations, challenges, and future directions in the development of vitreous substitutes, particularly the experimental and clinical use of a new artificial foldable capsular vitreous body.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.