ArticleBrain and behavior2015
Intraventricular cerebrospinal fluid temperature analysis using MR diffusion-weighted imaging thermometry in Parkinson's disease patients, multiple system atrophy patients, and healthy subjects.
Article in Brain and behavior, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- Brain temperature remains stable during the day: a study of diffusion-weighted imaging thermometry in healthy individuals.Neuroradiology · 2023Article
- DWI-based MR thermometry: could it discriminate Alzheimer's disease from mild cognitive impairment and healthy subjects?Neuroradiology · 2022Article
- Effects of motion and b-value on apparent temperature measurement by diffusion-based thermometry MRI: eye vitreous study.Medical physics · 2020Article
- CDK4 and CDK5 Inhibition Have Comparable Mild Hypothermia Effects in Preventing Drp1-Dependent Mitochondrial Fission and Neuron Death Induced by MPPMolecular neurobiology · 2020Article
- Optimal strategy for measuring intraventricular temperature using acceleration motion compensation diffusion-weighted imaging.Radiological physics and technology · 2020Article
- In Vivo Stability of Therapeutic Proteins.Pharmaceutical research · 2020Review
- Cold Exposure After Exercise Impedes the Neuroprotective Effects of Exercise on Thermoregulation and UCP4 Expression in an MPTP-Induced Parkinsonian Mouse Model.Frontiers in neuroscience · 2020Article
- Activating dopamine D2 receptors reduces brown adipose tissue thermogenesis induced by psychological stress and by activation of the lateral habenula.Scientific reports · 2019Article
- Altered coupling of spontaneous brain activities and brain temperature in patients with adolescent-onset, first-episode, drug-naïve schizophrenia.Neuroradiology · 2019Article
- Magnetic resonance thermometry and its biological applications - Physical principles and practical considerations.Progress in nuclear magnetic resonance spectroscopy · 2019Review
- Brain-core temperature of patients before and after orthotopic liver transplantation assessed by DWI thermometry.Japanese journal of radiology · 2018Article
- Assessment of brain core temperature using MR DWI-thermometry in Alzheimer disease patients compared to healthy subjects.Japanese journal of radiology · 2017Article
- A New Perspective for Parkinson's Disease: Circadian Rhythm.Neuroscience bulletin · 2017Review
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Authors and funding
15 authors.
Funding
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Abstract
purposeWe examined the temperature of the intraventricular cerebrospinal fluid (Tv) in patients with Parkinson's disease (PD) and those with multiple system atrophy (MSA) in comparison with healthy subjects, and we examined normal changes in this temperature with aging.
methodsTv was estimated by magnetic resonance (MR) diffusion-weighted imaging (DWI) thermometry in 36 PD patients (19 males, 17 females), 34 MSA patients (17 males, 17 females), 64 age-matched controls (27 men, 37 women), and 114 all-age adult controls (47 men, 67 women; 28-89 years old). The volume of lateral ventricles was also estimated using FreeSurfer in all subjects. Tv and ventricular volume data were compared among the PD and MSA patients and age-matched controls. We also evaluated the relationship between Tv and age in the 114 all-age controls, controlling for ventricular volume. Men and women were analyzed separately.
resultsThe male PD and MSA patients had significantly higher Tv values compared to the male controls, with no significant difference in ventricular volume among them. There was no significant difference in Tv between the female patients and controls. In the all-age male controls, there was a significant negative correlation between Tv and age controlling for ventricular volume, and this was not observed in the women.
conclusionDWI thermometry is a useful and easy method for demonstrating an altered intracranial environment in male patients and healthy controls, but not in females. DWI thermometry can thus be used to help to explore the pathophysiology of Parkinsonian syndromes and to differentiate individuals affected by neurodegenerative disease with autonomic dysfunction from those without it.
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